Reactome | TP53 binds the RRM2B gene

Schema > Reaction > Entries

TP53 binds the RRM2B gene Show undefined attributes

authored	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5632884] Orlic-Milacic, Marija, 2014-10-29
dbId	5632887
displayName	TP53 binds the RRM2B gene
edited	[InstanceEdit:5659776] Orlic-Milacic, Marija, 2014-12-23
eventOf	[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-5632892] TP53 stimulates transcription of RRM2B gene - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5632883] RRM2B Gene [nucleoplasm] [Complex:R-HSA-3209194] TP53 Tetramer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:111775] A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage [LiteratureReference:8856012] A ribonucleotide reductase gene is a transcriptional target of p53 and p73
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 binds the RRM2B gene
output	[Complex:R-HSA-5632886] TP53 Tetramer:RRM2B Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6804762] TP53 forms homotetramers - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5662800] Hwang, Paul M, 2014-12-30 [InstanceEdit:5662803] Kang, Ju-Gyeong, 2014-12-30 [InstanceEdit:5662801] Wang, Ping-yuan, 2014-12-30 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04 [InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5632887
summation	[Summation:5632888] TP53 (p53) binds the p53-binding site in the first intron of...
updateTrackers	[UpdateTracker:9783555] Update Tracker - [Reaction:5632887] TP53 binds the RRM2B gene - v56:[addLiteratureReference, modifyText] [UpdateTracker:9783986] Update Tracker - [Reaction:5632887] TP53 binds the RRM2B gene - v55:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9783555] Update Tracker - [Reaction:5632887] TP53 binds the RRM2B gene - v56:[addLiteratureReference, modifyText] [UpdateTracker:9783986] Update Tracker - [Reaction:5632887] TP53 binds the RRM2B gene - v55:[modifyText]
(precedingEvent)	[BlackBoxEvent:R-HSA-5632892] TP53 stimulates transcription of RRM2B gene
(hasEvent)	[Pathway:R-HSA-5628897] TP53 Regulates Metabolic Genes