Reactome | Cargo-carrying vesicles bud from the TGN

Schema > BlackBoxEvent > Entries

Cargo-carrying vesicles bud from the TGN Show undefined attributes

authored	[InstanceEdit:5620934] Rothfels, Karen, 2014-08-27
category	omitted
compartment	[Compartment:13949] Golgi-associated vesicle membrane
created	[InstanceEdit:5623523] Rothfels, Karen, 2014-09-12
dbId	5623525
displayName	Cargo-carrying vesicles bud from the TGN
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
eventOf	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium - Homo sapiens
followingEvent	[Reaction:R-HSA-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Homo sapiens
input	[Complex:R-HSA-5623447] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5623279] A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor [LiteratureReference:5623292] Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1 [LiteratureReference:5623326] Structural characteristics of BAR domain superfamily to sculpt the membrane [LiteratureReference:5623289] Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome [LiteratureReference:5623294] Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4 [LiteratureReference:5623300] Crosstalk of Arf and Rab GTPases en route to cilia
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Cargo-carrying vesicles bud from the TGN
orthologousEvent	[BlackBoxEvent:R-DME-5623525] Cargo-carrying vesicles bud from the TGN - Drosophila melanogaster [BlackBoxEvent:R-GGA-5623525] Cargo-carrying vesicles bud from the TGN - Gallus gallus [BlackBoxEvent:R-XTR-5623525] Cargo-carrying vesicles bud from the TGN - Xenopus tropicalis [BlackBoxEvent:R-SSC-5623525] Cargo-carrying vesicles bud from the TGN - Sus scrofa [BlackBoxEvent:R-BTA-5623525] Cargo-carrying vesicles bud from the TGN - Bos taurus [BlackBoxEvent:R-CFA-5623525] Cargo-carrying vesicles bud from the TGN - Canis familiaris [BlackBoxEvent:R-RNO-5623525] Cargo-carrying vesicles bud from the TGN - Rattus norvegicus [BlackBoxEvent:R-MMU-5623525] Cargo-carrying vesicles bud from the TGN - Mus musculus
output	[Complex:R-HSA-5623450] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane]
precedingEvent	[Reaction:R-HSA-5623521] RAB3IP stimulates nucleotide exchange on RAB8A - Homo sapiens
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-5623525
summation	[Summation:5623350] Membrane budding at the trans-Golgi network is promoted at l...

Referrals

(precedingEvent)	[Reaction:R-HSA-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex
(hasEvent)	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium

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