Reactome | The exocyst complex binds to RAB3IP in the ciliary targeting complex

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The exocyst complex binds to RAB3IP in the ciliary targeting complex Show undefined attributes

authored	[InstanceEdit:5620934] Rothfels, Karen, 2014-08-27
category	binding
compartment	[Compartment:13949] Golgi-associated vesicle membrane
created	[InstanceEdit:5623523] Rothfels, Karen, 2014-09-12
dbId	5623524
displayName	The exocyst complex binds to RAB3IP in the ciliary targeting complex
edited	[InstanceEdit:5626894] Jassal, Bijay, 2014-10-13
eventOf	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-5623527] VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane - Homo sapiens
input	[Complex:R-HSA-5623453] exocyst complex [cytosol] [Complex:R-HSA-5623450] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5623281] A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesis [LiteratureReference:5623300] Crosstalk of Arf and Rab GTPases en route to cilia [LiteratureReference:5623319] Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo [LiteratureReference:5623334] The exocyst localizes to the primary cilium in MDCK cells [LiteratureReference:5623336] The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro [LiteratureReference:5623313] Rabs and the exocyst in ciliogenesis, tubulogenesis and beyond [LiteratureReference:5626637] Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways [LiteratureReference:5623304] Exorcising the exocyst complex
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	The exocyst complex binds to RAB3IP in the ciliary targeting complex
orthologousEvent	[Reaction:R-CEL-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Caenorhabditis elegans [Reaction:R-DME-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Drosophila melanogaster [Reaction:R-GGA-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Gallus gallus [Reaction:R-XTR-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Xenopus tropicalis [Reaction:R-SSC-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Sus scrofa [Reaction:R-BTA-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Bos taurus [Reaction:R-CFA-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Canis familiaris [Reaction:R-RNO-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Rattus norvegicus [Reaction:R-MMU-5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - Mus musculus
output	[Complex:R-HSA-5623455] exocyst complex:RAB8A:GTP:RAB3IP:RAB11:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane]
precedingEvent	[BlackBoxEvent:R-HSA-5623525] Cargo-carrying vesicles bud from the TGN - Homo sapiens
releaseDate	2014-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5637996] Lorentzen, Esben, 2014-11-10 [InstanceEdit:5638370] Goncalves, Joao, 2014-11-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5623524
summation	[Summation:5623354] RAB3IP interacts directly with the EXOC6/SEC15 component of ...
systematicName	RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins binds exocyst complex forming RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins:exocyst complex
updateTrackers	[UpdateTracker:9964648] Update Tracker - [Reaction:5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - v94:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9964648] Update Tracker - [Reaction:5623524] The exocyst complex binds to RAB3IP in the ciliary targeting complex - v94:[modifyText]
(precedingEvent)	[BlackBoxEvent:R-HSA-5623527] VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane
(hasEvent)	[Pathway:R-HSA-5620916] VxPx cargo-targeting to cilium

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