Reactome | CD209 binds ManLAM

Schema > Reaction > Entries

authored	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5621584] Garapati, P V, 2014-09-01
dbId	5621606
displayName	CD209 binds ManLAM
edited	[InstanceEdit:5660664] Garapati, P V, 2015-01-04
eventOf	[Pathway:R-HSA-5621575] CD209 (DC-SIGN) signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-5621573] CD209 activate GTPase RAS - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2079928] CD209 [plasma membrane] [SimpleEntity:R-ALL-5621607] ManLAM [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5621576] Mycobacteria target DC-SIGN to suppress dendritic cell function
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CD209 binds ManLAM DC-SIGN binds ManLAM
output	[Complex:R-HSA-5621611] CD209:ManLAM [plasma membrane]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5621606
summation	[Summation:5621600] CD209 (DC-SIGN) interacts with pathogens through either mann...

(hasEvent)	[Pathway:R-HSA-5621575] CD209 (DC-SIGN) signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-5621573] CD209 activate GTPase RAS

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