Reactome | RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]

Schema > Complex > Entries

RNA Polymerase II holoenzyme complex (generic) [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:203921] DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-5617453] HOXD1 active chromatin [nucleoplasm] - Homo sapiens [Complex:R-HSA-5617873] atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] - Homo sapiens [Complex:R-HSA-5693638] HOXB1:PBX1:PKNOX1 and MEIS1 at active HOXB1 chromatin [nucleoplasm] - Homo sapiens [Complex:R-HSA-5617448] atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-5617445] HOXD1 chromatin is activated - Homo sapiens [BlackBoxEvent:R-HSA-5621002] HOXB1 activates HOXB2 expression - Homo sapiens [BlackBoxEvent:R-HSA-5617641] MAFB (KREISLER) and HOXB1:PBX1:PKNOX1 (HOXB1:PBX1:PREP1) activate HOXA3 expression - Homo sapiens [BlackBoxEvent:R-HSA-5617484] EGR2 (KROX20) activates HOXA2 expression - Homo sapiens [BlackBoxEvent:R-HSA-5617650] HOXD3 chromatin is activated - Homo sapiens [BlackBoxEvent:R-HSA-5617492] EGR2 (KROX20) activates HOXB2 expression - Homo sapiens [BlackBoxEvent:R-HSA-5621010] HOXB1 activates HOXA2 expression - Homo sapiens [BlackBoxEvent:R-HSA-5617896] Retinoic acid activates HOXD4 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617887] HOXC4 chromatin is activated - Homo sapiens [BlackBoxEvent:R-HSA-5617862] Retinoic acid activates HOXA4 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617452] Retinoic acid activates HOXB1 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617431] Retinoic acid activates HOXA1 chromatin - Homo sapiens [BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin - Homo sapiens
created	[InstanceEdit:209681] Gopinathrao, G, 2008-01-02 21:49:21
crossReference	[DatabaseIdentifier:11891478] ComplexPortal:CPX-7481
dbId	209680
displayName	RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-63502] POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63504] POLR2B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63506] POLR2C [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63508] POLR2D [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83713] POLR2E [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83714] POLR2F [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63517] POLR2G [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63523] POLR2H [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63525] POLR2I [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63531] POLR2J [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-63537] POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83715] POLR2L [nucleoplasm]
inDisease	false
modified	[InstanceEdit:11891188] Wright, Adam, 2024-03-11
name	RNA Polymerase II holoenzyme complex (generic)
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-209680

Referrals

(hasComponent)	[Complex:R-HSA-5617453] HOXD1 active chromatin [nucleoplasm] [Complex:R-HSA-5617663] HOXD3 active chromatin [nucleoplasm] [Complex:R-HSA-5617651] MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm] [Complex:R-HSA-5617873] atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] [Complex:R-HSA-5617489] EGR2 at active HOXB2 chromatin [nucleoplasm] [Complex:R-HSA-5617448] atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] [Complex:R-HSA-5621001] HOXB1:PBX1:PKNOX1 at active HOXA2 chromatin [nucleoplasm] [Complex:R-HSA-5693638] HOXB1:PBX1:PKNOX1 and MEIS1 at active HOXB1 chromatin [nucleoplasm] [Complex:R-HSA-5617470] atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] [Complex:R-HSA-5617861] atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm] [Complex:R-HSA-5617870] HOXC4 active chromatin [nucleoplasm] [Complex:R-HSA-5617888] atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] [Complex:R-HSA-5617671] MAFB:JUN and EGR2 at active HOXB3 chromatin [nucleoplasm] [Complex:R-HSA-5617477] EGR2 at active HOXA2 chromatin [nucleoplasm] [Complex:R-HSA-5621009] HOXB1:PBX1:MEIS1,PKNOX1 at active HOXB2 chromatin [nucleoplasm]
(input)	[BlackBoxEvent:R-HSA-5617445] HOXD1 chromatin is activated [BlackBoxEvent:R-HSA-5617650] HOXD3 chromatin is activated [BlackBoxEvent:R-HSA-5621002] HOXB1 activates HOXB2 expression [BlackBoxEvent:R-HSA-5617641] MAFB (KREISLER) and HOXB1:PBX1:PKNOX1 (HOXB1:PBX1:PREP1) activate HOXA3 expression [BlackBoxEvent:R-HSA-5617862] Retinoic acid activates HOXA4 chromatin [BlackBoxEvent:R-HSA-5617492] EGR2 (KROX20) activates HOXB2 expression [BlackBoxEvent:R-HSA-5617431] Retinoic acid activates HOXA1 chromatin [BlackBoxEvent:R-HSA-5621010] HOXB1 activates HOXA2 expression [BlackBoxEvent:R-HSA-5617452] Retinoic acid activates HOXB1 chromatin [BlackBoxEvent:R-HSA-5617896] Retinoic acid activates HOXD4 chromatin [BlackBoxEvent:R-HSA-5617887] HOXC4 chromatin is activated [BlackBoxEvent:R-HSA-5617859] Retinoic acid activates HOXB4 chromatin [BlackBoxEvent:R-HSA-5617484] EGR2 (KROX20) activates HOXA2 expression
(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-5634074] Positive gene expression regulation by 'atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634094] Positive gene expression regulation by 'HOXD1 active chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634087] Positive gene expression regulation by 'HOXD3 active chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634090] Positive gene expression regulation by 'HOXC4 active chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634068] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5693647] Positive gene expression regulation by 'HOXB1:PBX1:PKNOX1 and MEIS1 at active HOXB1 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634072] Positive gene expression regulation by 'atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634091] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634093] Positive gene expression regulation by 'atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634070] Positive gene expression regulation by 'MAFB:JUN and EGR2 at active HOXB3 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634071] Positive gene expression regulation by 'EGR2 at active HOXA2 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634076] Positive gene expression regulation by 'HOXB1:PBX1:PKNOX1 at active HOXA2 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634079] Positive gene expression regulation by 'EGR2 at active HOXB2 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634075] Positive gene expression regulation by 'HOXB1:PBX1:MEIS1,PKNOX1 at active HOXB2 chromatin [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-5634092] Positive gene expression regulation by 'MAFB, HOXB1:PBX1:PKNOX1 at active HOXA3 chromatin [nucleoplasm]'
(physicalEntity)	[CatalystActivity:203921] DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]

© 2024 Reactome

Cite Us!