Reactome | p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane

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p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane Show undefined attributes

authored	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
dbId	5607755
displayName	p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane
edited	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
eventOf	[Pathway:R-HSA-5607764] CLEC7A (Dectin-1) signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5607631] p-Y753,Y759-PLCG2 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5607205] Tyrosine phosphorylation and translocation of phospholipase C-gamma 2 in polymorphonuclear leukocytes treated with pervanadate [LiteratureReference:1169037] Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane
orthologousEvent	[Reaction:R-PFA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Plasmodium falciparum [Reaction:R-SCE-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Saccharomyces cerevisiae [Reaction:R-SPO-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Schizosaccharomyces pombe [Reaction:R-DDI-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Dictyostelium discoideum [Reaction:R-CEL-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Caenorhabditis elegans [Reaction:R-DME-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Drosophila melanogaster [Reaction:R-GGA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Gallus gallus [Reaction:R-XTR-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Xenopus tropicalis [Reaction:R-SSC-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Sus scrofa [Reaction:R-BTA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Bos taurus [Reaction:R-CFA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Canis familiaris [Reaction:R-RNO-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Rattus norvegicus [Reaction:R-MMU-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-5607640] p-Y753,Y759-PLCG2 [plasma membrane]
precedingEvent	[Reaction:R-HSA-5607745] 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG - Homo sapiens
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5607755
summation	[Summation:5607597] Tyrosine-phosphorylated Phospholipase C-gamma 2 (PLCG2) tran...

Referrals

(hasEvent)	[Pathway:R-HSA-5607764] CLEC7A (Dectin-1) signaling
(precedingEvent)	[Reaction:R-HSA-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2