Reactome | p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane

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p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane Show undefined attributes

category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11066741
displayName	p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane
eventOf	[Pathway:R-SPO-5607764] CLEC7A (Dectin-1) signaling - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2 - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-5607631] phospho-p-Y753,Y759-PLCG2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane
output	[EntityWithAccessionedSequence:R-SPO-5607640] phospho-p-Y753,Y759-PLCG2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-5607755
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-5607764] CLEC7A (Dectin-1) signaling
(precedingEvent)	[Reaction:R-SPO-5607735] p-Y753,Y759-PLCG2 hydrolyses PIP2
(inferredTo)	[Reaction:R-HSA-5607755] p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane

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