Reactome | PDIA3 [endoplasmic reticulum lumen]

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PDIA3 [endoplasmic reticulum lumen] Show undefined attributes

compartment	[Compartment:17957] endoplasmic reticulum lumen
componentOf	[Complex:R-HSA-909545] unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone:ERp57 [endoplasmic reticulum lumen] - Homo sapiens [Complex:R-HSA-901040] unfolded protein:glycan:chaperone:ERp57 [endoplasmic reticulum lumen] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-901047] Binding of ERp57 - Homo sapiens [Reaction:R-HSA-983148] Interaction of Erp57 with MHC class I HC - Homo sapiens
created	[InstanceEdit:901079] Jassal, B, 2010-07-02
dbId	901028
displayName	PDIA3 [endoplasmic reticulum lumen]
endCoordinate	505
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-983088] Erp57 [endoplasmic reticulum lumen] - Mus musculus [EntityWithAccessionedSequence:R-RNO-901028] Pdia3 [endoplasmic reticulum lumen] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-901028] PDIA3 [endoplasmic reticulum lumen] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-901028] PDIA3 [endoplasmic reticulum lumen] - Bos taurus [EntityWithAccessionedSequence:R-SSC-901028] PDIA3 [endoplasmic reticulum lumen] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-901028] pdia8 [endoplasmic reticulum lumen] - Danio rerio [EntityWithAccessionedSequence:R-DRE-901028-2] pdia7 [endoplasmic reticulum lumen] - Danio rerio [DefinedSet:R-DRE-901028-3] Homologues of PDIA3 [endoplasmic reticulum lumen] - Danio rerio [EntityWithAccessionedSequence:R-XTR-901028] pdia3 [endoplasmic reticulum lumen] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-901028] PDIA3 [endoplasmic reticulum lumen] - Gallus gallus [EntityWithAccessionedSequence:R-DME-901028] ERp60 [endoplasmic reticulum lumen] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-901028] pdi-3 [endoplasmic reticulum lumen] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-901028] pdi2 [endoplasmic reticulum lumen] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-901028] PDIA3 [endoplasmic reticulum lumen] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-901028] PDI1 [endoplasmic reticulum lumen] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-901028] PDIA3 [endoplasmic reticulum lumen] - Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	PDIA3 ERp57 Protein disulfide-isomerase A3 PDIA3_HUMAN
positivelyRegulates	[PositiveRegulation:9945586] Positive regulation by 'PDIA3 [endoplasmic reticulum lumen]'
producedByEvent	[Reaction:R-HSA-548890] Removal of the third glucose by glucosidase II and release from the chaperone - Homo sapiens [Reaction:R-HSA-983161] Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P30101] UniProt:P30101 PDIA3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-901028
startCoordinate	25

Referrals

(regulator)	[PositiveRegulation:9945586] Positive regulation by 'PDIA3 [endoplasmic reticulum lumen]'
(hasComponent)	[Complex:R-HSA-909545] unfolded protein:(Glc)1 (GlcNAc)2 (Man)9 (Asn)1:chaperone:ERp57 [endoplasmic reticulum lumen] [Complex:R-HSA-901040] unfolded protein:glycan:chaperone:ERp57 [endoplasmic reticulum lumen] [Complex:R-HSA-983119] MHC class I HC:Calnexin/BiP:Erp57 [lumenal side of endoplasmic reticulum membrane] [Complex:R-HSA-983136] MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane]
(input)	[Reaction:R-HSA-901047] Binding of ERp57 [Reaction:R-HSA-983148] Interaction of Erp57 with MHC class I HC
(output)	[Reaction:R-HSA-548890] Removal of the third glucose by glucosidase II and release from the chaperone [Reaction:R-HSA-983161] Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex

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