Reactome | CREB1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

CREB1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-2399996] AKT1 E17K mutant phosphorylates CREB1 - Homo sapiens [Reaction:R-HSA-199917] MAPKAPK2 phosphorylates CREB at Serine 133 - Homo sapiens [Reaction:R-HSA-199895] RSK1/2/3 phosphorylates CREB at Serine 119 - Homo sapiens [Reaction:R-HSA-111919] PKA phosphorylates CREB1 - Homo sapiens [Reaction:R-HSA-199935] MSK1 activates CREB - Homo sapiens [Reaction:R-HSA-9612501] SGK phosphorylates CREB1 - Homo sapiens [Reaction:R-HSA-442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) - Homo sapiens [Reaction:R-HSA-111912] CaMK4 phosphorylates CREB1 - Homo sapiens [Reaction:R-HSA-199298] AKT phosphorylates CREB1 - Homo sapiens
dbId	52777
displayName	CREB1 [nucleoplasm]
endCoordinate	341
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9021874] Creb1 [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-52777] Creb1 [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-52777] CREB1 [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-52777] CREB1 [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-52777] CREB1 [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-52777] creb1b [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-52777] creb1 [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-52777] CREB1 [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-52777] CrebB [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-52777] crh-1 [nucleoplasm] - Caenorhabditis elegans
maxDepth	1
modified	[InstanceEdit:9857428] Orlic-Milacic, Marija, 2024-01-04
name	CREB1 CREB CREB-A cAMP-response element binding protein cAMP response element binding protein
positivelyRegulates	[PositiveGeneExpressionRegulation:9621069] Positive gene expression regulation by 'CREB1 [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-HSA-9021847] CREB1 gene expression is stimulated by MECP2 - Homo sapiens
referenceEntity	[ReferenceIsoform:uniprot:P16220-1] UniProt:P16220-1 CREB1
referenceType	ReferenceIsoform
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-52777
startCoordinate	1
updateTrackers	[UpdateTracker:9872865] Update Tracker - [EntityWithAccessionedSequence:52777] CREB1 [nucleoplasm] - v42:[addName, modifyEndCoordinate] [UpdateTracker:9906441] Update Tracker - [EntityWithAccessionedSequence:52777] CREB1 [nucleoplasm] - v87:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9872865] Update Tracker - [EntityWithAccessionedSequence:52777] CREB1 [nucleoplasm] - v42:[addName, modifyEndCoordinate] [UpdateTracker:9906441] Update Tracker - [EntityWithAccessionedSequence:52777] CREB1 [nucleoplasm] - v87:[modifyEndCoordinate]
(input)	[Reaction:R-HSA-2399996] AKT1 E17K mutant phosphorylates CREB1 [Reaction:R-HSA-199917] MAPKAPK2 phosphorylates CREB at Serine 133 [Reaction:R-HSA-199895] RSK1/2/3 phosphorylates CREB at Serine 119 [Reaction:R-HSA-111919] PKA phosphorylates CREB1 [Reaction:R-HSA-199935] MSK1 activates CREB [Reaction:R-HSA-9612501] SGK phosphorylates CREB1 [Reaction:R-HSA-442724] Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) [Reaction:R-HSA-111912] CaMK4 phosphorylates CREB1 [Reaction:R-HSA-199298] AKT phosphorylates CREB1
(output)	[BlackBoxEvent:R-HSA-9021847] CREB1 gene expression is stimulated by MECP2
(activeUnit)	[PositiveGeneExpressionRegulation:9620411] Positive gene expression regulation by 'p-S133-CREB1:MEF2D:SRF:ARC gene [nucleoplasm]'
(regulator)	[PositiveGeneExpressionRegulation:9621069] Positive gene expression regulation by 'CREB1 [nucleoplasm]'

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