Reactome | LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]

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LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5205648] ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5205663] LC3 binds the autophagosome membrane Atg5-Atg12 complex - Homo sapiens
created	[InstanceEdit:5205680] Gillespie, Marc E, 2013-12-04
dbId	5205670
displayName	LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
hasComponent	[Complex:R-HSA-5205659] K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] [DefinedSet:R-HSA-5205658] LC3 [cytosol]
inDisease	false
includedLocation	[Compartment:17906] mitochondrial outer membrane
inferredTo	[Complex:R-MMU-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Mus musculus [Complex:R-RNO-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Rattus norvegicus [Complex:R-BTA-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Bos taurus [Complex:R-SSC-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Sus scrofa [Complex:R-DRE-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Danio rerio [Complex:R-XTR-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Xenopus tropicalis [Complex:R-GGA-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Gallus gallus [Complex:R-CEL-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Caenorhabditis elegans
isChimeric	false
maxDepth	4
name	LC3:K48polyUB Mitophagy Substrates:SQSTM1
producedByEvent	[Reaction:R-HSA-5205649] p62 links damaged mitochondria to LC3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5205670

Referrals

(output)	[Reaction:R-HSA-5205649] p62 links damaged mitochondria to LC3
(hasComponent)	[Complex:R-HSA-5205648] ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle]
(input)	[Reaction:R-HSA-5205663] LC3 binds the autophagosome membrane Atg5-Atg12 complex

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