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LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
Stable Identifier
R-HSA-5205670
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Selective autophagy (Homo sapiens)
Mitophagy (Homo sapiens)
Pink/Parkin Mediated Mitophagy (Homo sapiens)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
p62 links damaged mitochondria to LC3 (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
Participants
components
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
Participant Of
output
p62 links damaged mitochondria to LC3
hasComponent
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle]
input
LC3 binds the autophagosome membrane Atg5-Atg12 complex
Inferred To
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Bos taurus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Caenorhabditis elegans)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Canis familiaris)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Danio rerio)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Drosophila melanogaster)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Gallus gallus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Mus musculus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Rattus norvegicus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Sus scrofa)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Xenopus tropicalis)
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