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LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
Stable Identifier
R-HSA-5205670
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Selective autophagy (Homo sapiens)
Mitophagy (Homo sapiens)
PINK1-PRKN Mediated Mitophagy (Homo sapiens)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
p62 links damaged mitochondria to LC3 (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
Participants
components
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
(Homo sapiens)
LC3 [cytosol]
(Homo sapiens)
Participates
as an output of
p62 links damaged mitochondria to LC3 (Homo sapiens)
as a component of
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Homo sapiens)
as an input of
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)
Inferred To
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Bos taurus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Caenorhabditis elegans)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Canis familiaris)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Danio rerio)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Drosophila melanogaster)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Gallus gallus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Mus musculus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Rattus norvegicus)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Sus scrofa)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
(Xenopus tropicalis)
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