Reactome | LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-5205648] ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5205663] LC3 binds the autophagosome membrane Atg5-Atg12 complex - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10511542
displayName	LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]
hasComponent	[Complex:R-SSC-5205659] K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] [DefinedSet:R-SSC-5205658] LC3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] - Homo sapiens
maxDepth	4
name	LC3:K48polyUB Mitophagy Substrates:SQSTM1
producedByEvent	[Reaction:R-SSC-5205649] p62 links damaged mitochondria to LC3 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-5205670
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-5205663] LC3 binds the autophagosome membrane Atg5-Atg12 complex
(output)	[Reaction:R-SSC-5205649] p62 links damaged mitochondria to LC3
(hasComponent)	[Complex:R-SSC-5205648] ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle]
(inferredTo)	[Complex:R-HSA-5205670] LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol]

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