Reactome | PTK2B binds JAK3

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PTK2B binds JAK3 Show undefined attributes

authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:508514] Jupe, S, 2010-02-12
dbId	508513
displayName	PTK2B binds JAK3
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
eventOf	[Pathway:R-HSA-9020558] Interleukin-2 signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-508451] PTK2B is phosphorylated - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-451893] JAK3 [cytosol] [EntityWithAccessionedSequence:R-HSA-390932] PTK2B [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:508442] Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	PTK2B binds JAK3 Pyk2 associates with Jak3
orthologousEvent	[Reaction:R-GGA-508513] PTK2B binds JAK3 - Gallus gallus [Reaction:R-DRE-508513] PTK2B binds JAK3 - Danio rerio [Reaction:R-SSC-508513] PTK2B binds JAK3 - Sus scrofa [Reaction:R-BTA-508513] PTK2B binds JAK3 - Bos taurus [Reaction:R-CFA-508513] PTK2B binds JAK3 - Canis familiaris [Reaction:R-RNO-508513] PTK2B binds JAK3 - Rattus norvegicus [Reaction:R-MMU-508513] PTK2B binds JAK3 - Mus musculus
output	[Complex:R-HSA-508512] JAK3:PYK2 [cytosol]
releaseDate	2011-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-508513
summation	[Summation:508511] The proline-rich tyrosine kinase 2 (PYK2) is a nonreceptor p...

Referrals

(hasEvent)	[Pathway:R-HSA-9020558] Interleukin-2 signaling
(precedingEvent)	[BlackBoxEvent:R-HSA-508451] PTK2B is phosphorylated

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