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Schema
>
BlackBoxEvent
>
Entries
PRICKLE1 is degraded by the proteasome
Show undefined attributes
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authored
[InstanceEdit:4568841] Rothfels, K, 2013-09-18
catalystActivity
[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
category
omitted
compartment
[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created
[InstanceEdit:4608853] Rothfels, K, 2013-09-23
dbId
4608855
displayName
PRICKLE1 is degraded by the proteasome
edited
[InstanceEdit:4663813] Matthews, L, 2013-10-07
eventOf
[Pathway:R-HSA-4608870] Asymmetric localization of PCP proteins - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-4608820] ub-PRICKLE1 [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:4608829] Regulation of planar cell polarity by Smurf ubiquitin ligases
maxDepth
1
modified
[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name
PRICKLE1 is degraded by the proteasome
orthologousEvent
[BlackBoxEvent:R-CEL-4608855] PRICKLE1 is degraded by the proteasome - Caenorhabditis elegans
[BlackBoxEvent:R-DME-4608855] PRICKLE1 is degraded by the proteasome - Drosophila melanogaster
[BlackBoxEvent:R-GGA-4608855] PRICKLE1 is degraded by the proteasome - Gallus gallus
[BlackBoxEvent:R-XTR-4608855] PRICKLE1 is degraded by the proteasome - Xenopus tropicalis
[BlackBoxEvent:R-DRE-4608855] PRICKLE1 is degraded by the proteasome - Danio rerio
[BlackBoxEvent:R-SSC-4608855] PRICKLE1 is degraded by the proteasome - Sus scrofa
[BlackBoxEvent:R-BTA-4608855] PRICKLE1 is degraded by the proteasome - Bos taurus
[BlackBoxEvent:R-CFA-4608855] PRICKLE1 is degraded by the proteasome - Canis familiaris
[BlackBoxEvent:R-RNO-4608855] PRICKLE1 is degraded by the proteasome - Rattus norvegicus
[BlackBoxEvent:R-MMU-4608855] PRICKLE1 is degraded by the proteasome - Mus musculus
precedingEvent
[Reaction:R-HSA-4608852] SMURF1/2 ubiquitinates PRICKLE1 - Homo sapiens
releaseDate
2013-12-04
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5099870] Kikuchi, Akira, 2013-11-12
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-4608855
summation
[Summation:4608846] Localized degradation of ub-PRICKLE1 contributes to asymmetr...
Referrals
(hasEvent)
[Pathway:R-HSA-4608870] Asymmetric localization of PCP proteins
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