Reactome | IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane]

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IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-452107] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] - Homo sapiens [Complex:R-HSA-452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-452108] Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment - Homo sapiens [Reaction:R-HSA-452091] Phosphorylation of IL2RB Y338 enables SHC recruitment - Homo sapiens
created	[InstanceEdit:452117] Jupe, S, 2010-01-15
dbId	452119
displayName	IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-447099] IL2 [extracellular region] [EntityWithAccessionedSequence:R-HSA-450046] IL2RA [plasma membrane] [Complex:R-HSA-451911] IL2RG:JAK3 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-451921] p-Y-JAK1 [cytosol] [EntityWithAccessionedSequence:R-HSA-452093] p-Y364,Y418,Y536-IL2RB [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - Mus musculus [Complex:R-RNO-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - Canis familiaris [Complex:R-BTA-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - Bos taurus [Complex:R-SSC-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - Sus scrofa
isChimeric	false
maxDepth	3
modified	[InstanceEdit:919403] Jupe, S, 2010-08-04
name	IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3
producedByEvent	[Reaction:R-HSA-919404] Phosphorylated STAT5 is released - Homo sapiens [Reaction:R-HSA-452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-452119
updateTrackers	[UpdateTracker:9871218] Update Tracker - [Complex:452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9872380] Update Tracker - [Complex:452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - v41:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9871218] Update Tracker - [Complex:452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - v39:[updateContainedComponent] [UpdateTracker:9872380] Update Tracker - [Complex:452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] - v41:[updateContainedComponent]
(input)	[Reaction:R-HSA-452108] Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment [Reaction:R-HSA-452091] Phosphorylation of IL2RB Y338 enables SHC recruitment
(hasComponent)	[Complex:R-HSA-452107] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane] [Complex:R-HSA-507943] IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane] [Complex:R-HSA-452095] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHC [plasma membrane]
(output)	[Reaction:R-HSA-919404] Phosphorylated STAT5 is released [Reaction:R-HSA-452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB

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