Reactome | Phosphorylated STAT5 is released

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Phosphorylated STAT5 is released Show undefined attributes

authored	[InstanceEdit:744679] Ray, KP, 2010-05-17
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:919403] Jupe, S, 2010-08-04
dbId	919404
displayName	Phosphorylated STAT5 is released
edited	[InstanceEdit:924611] Jupe, S, 2010-08-06
eventOf	[Pathway:R-HSA-9020558] Interleukin-2 signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-452102] p-STAT5 dimerizes - Homo sapiens
input	[Complex:R-HSA-507943] IL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:919407] A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation
maxDepth	1
modified	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
name	Phosphorylated STAT5 is released
orthologousEvent	[Reaction:R-SSC-919404] Phosphorylated STAT5 is released - Sus scrofa [Reaction:R-BTA-919404] Phosphorylated STAT5 is released - Bos taurus [Reaction:R-CFA-919404] Phosphorylated STAT5 is released - Canis familiaris [Reaction:R-RNO-919404] Phosphorylated STAT5 is released - Rattus norvegicus [Reaction:R-MMU-919404] Phosphorylated STAT5 is released - Mus musculus
output	[Complex:R-HSA-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] [DefinedSet:R-HSA-507929] p-STAT5A, p-STAT5B [cytosol]
precedingEvent	[Reaction:R-HSA-452097] Recruited STAT5 is phosphorylated - Homo sapiens
releaseDate	2011-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1213492] Villarino, A, 2011-02-11 [InstanceEdit:1233246] Dooms, H, 2011-03-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-919404
summation	[Summation:919408] Deletion mutants have demonstrated that STAT dimerization ca...

Referrals

(hasEvent)	[Pathway:R-HSA-9020558] Interleukin-2 signaling
(precedingEvent)	[Reaction:R-HSA-452102] p-STAT5 dimerizes

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