Reactome | TBK1, IKBKE [cytosol]

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TBK1, IKBKE [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-933479] dsRNA:DDX58/IFIH1:MAVS:TRAF2/TRAF6:TANK:TBK1/IKBKE [mitochondrial outer membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9705137] TBK1 or IKBKE forms homodimers - Homo sapiens [Reaction:R-HSA-9817411] TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex - Homo sapiens [Reaction:R-HSA-9817411] TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex - Homo sapiens [Reaction:R-HSA-9705145] TBK1, IKBKE form homodimers - Homo sapiens [Reaction:R-HSA-937337] TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination - Homo sapiens
created	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
dbId	450329
displayName	TBK1, IKBKE [cytosol]
hasMember	[EntityWithAccessionedSequence:R-HSA-450225] IKBKE [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-166267] TBK1 [cytosol] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-450329] TBK1, IKBKE [cytosol] - Mus musculus [DefinedSet:R-RNO-450329] TBK1, IKBKE [cytosol] - Rattus norvegicus [DefinedSet:R-CFA-450329] TBK1, IKBKE [cytosol] - Canis familiaris [DefinedSet:R-BTA-450329] TBK1, IKBKE [cytosol] - Bos taurus [DefinedSet:R-SSC-450329] TBK1, IKBKE [cytosol] - Sus scrofa [DefinedSet:R-GGA-450329] TBK1, IKBKE [cytosol] - Gallus gallus
maxDepth	2
modified	[InstanceEdit:9730455] Shamovsky, Veronica, 2021-05-07
name	TBK1, IKBKE IKK related kinases TBK1/IKK epsilon
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-450329
updateTrackers	[UpdateTracker:9902288] Update Tracker - [DefinedSet:450329] TBK1, IKBKE [cytosol] - v77:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9902288] Update Tracker - [DefinedSet:450329] TBK1, IKBKE [cytosol] - v77:[addName]
(input)	[Reaction:R-HSA-9817411] TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex [Reaction:R-HSA-9705145] TBK1, IKBKE form homodimers [Reaction:R-HSA-937337] TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination [Reaction:R-HSA-9705137] TBK1 or IKBKE forms homodimers
(hasComponent)	[Complex:R-HSA-933479] dsRNA:DDX58/IFIH1:MAVS:TRAF2/TRAF6:TANK:TBK1/IKBKE [mitochondrial outer membrane] [Complex:R-HSA-937333] TAX1BP1:TNFAIP3:TBK1/IKBKE [cytosol] [Complex:R-HSA-918196] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:TBK1/IKBKE [mitochondrial outer membrane] [Complex:R-HSA-918197] TBK1/IKBKE:SIKE1 [cytosol]
(activeUnit)	[CatalystActivity:933524] protein serine/threonine kinase activity of dsRNA:DDX58/IFIH1:MAVS:TRAF2/TRAF6:TANK:TBK1/IKBKE:IRF7 [mitochondrial outer membrane]

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