Reactome | SUFU [cytosol]

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SUFU [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5621780] GLI:SUFU [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5610723] GLI proteins bind SUFU - Homo sapiens
created	[InstanceEdit:445454] Jupe, S, 2009-10-30
dbId	445455
displayName	SUFU [cytosol]
endCoordinate	484
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-5610427] Sufu [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-445455] Sufu [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-445455] SUFU [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-445455] SUFU [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-445455] SUFU [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-445455] sufu [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-445455] sufu [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-445455] SUFU [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-445455] Su(fu) [cytosol] - Drosophila melanogaster
maxDepth	1
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	SUFU Suppressor of fused homolog SUFU_HUMAN
producedByEvent	[BlackBoxEvent:R-NUL-5610751] Gli2is degraded by the proteasome - Homo sapiens [BlackBoxEvent:R-HSA-5610757] GLI2 is degraded by the proteasome - Homo sapiens [BlackBoxEvent:R-HSA-5610760] GLI1 is degraded by the proteasome after ubiquitination by ITCH - Homo sapiens [BlackBoxEvent:R-HSA-5610758] GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP - Homo sapiens [BlackBoxEvent:R-HSA-5610754] GLI3 is partially degraded by the proteasome to yield the GLI3 repressor - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UMX1] UniProt:Q9UMX1 SUFU
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-445455
startCoordinate	1

Referrals

(output)	[BlackBoxEvent:R-NUL-5610751] Gli2is degraded by the proteasome [BlackBoxEvent:R-HSA-5610757] GLI2 is degraded by the proteasome [BlackBoxEvent:R-HSA-5610760] GLI1 is degraded by the proteasome after ubiquitination by ITCH [BlackBoxEvent:R-HSA-5610758] GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP [BlackBoxEvent:R-HSA-5610754] GLI3 is partially degraded by the proteasome to yield the GLI3 repressor
(input)	[Reaction:R-HSA-5610723] GLI proteins bind SUFU
(hasComponent)	[Complex:R-HSA-5621780] GLI:SUFU [cytosol]

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