Reactome | Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites

Schema > Reaction > Entries

Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites Show undefined attributes

authored	[InstanceEdit:210542] Mahajan, SS, 2008-01-14 16:01:52
catalystActivity	[CatalystActivity:139850] calcium,diacylglycerol-dependent serine/threonine kinase activity of Activated conventional protein kinase C [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:416637] Mahajan, SS, 2009-03-30 19:54:28
dbId	416639
displayName	Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
edited	[InstanceEdit:422465] Mahajan, SS, 2009-05-31 11:49:00
eventOf	[Pathway:R-HSA-416993] Trafficking of GluR2-containing AMPA receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-421007] Endocytosis of Ca impermeable AMPA receptors - Homo sapiens [Reaction:R-HSA-416985] Trafficking of GluR2-containing AMPA receptors to synapse - Homo sapiens
input	[Complex:R-HSA-416629] AP2 complex [endocytic vesicle membrane] [SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-HSA-416323] Ca impermeable AMPA receptors [endocytic vesicle membrane] [DefinedSet:R-HSA-416636] GRIP1/GRIP2 [cytosol] [EntityWithAccessionedSequence:R-HSA-417017] PICK1 [endocytic vesicle membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:421008] PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
orthologousEvent	[Reaction:R-MMU-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Mus musculus [Reaction:R-DME-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Drosophila melanogaster [Reaction:R-GGA-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Gallus gallus [Reaction:R-DRE-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Danio rerio [Reaction:R-SSC-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Sus scrofa [Reaction:R-BTA-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Bos taurus [Reaction:R-RNO-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Rattus norvegicus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-416629] AP2 complex [endocytic vesicle membrane] [DefinedSet:R-HSA-399713] Ca impermeable AMPA receptors [plasma membrane] [DefinedSet:R-HSA-416631] GRIP1/GRIP2 [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol] [EntityWithAccessionedSequence:R-HSA-416989] PICK1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-421007] Endocytosis of Ca impermeable AMPA receptors - Homo sapiens
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:421048] Ziff, EB, 2009-05-15 16:23:37
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-416639
summation	[Summation:421011] GluR2 containing AMPA receptors are trafficked to the plasma...

Referrals

(hasEvent)	[Pathway:R-HSA-416993] Trafficking of GluR2-containing AMPA receptors
(precedingEvent)	[Reaction:R-HSA-416985] Trafficking of GluR2-containing AMPA receptors to synapse [Reaction:R-HSA-421007] Endocytosis of Ca impermeable AMPA receptors