Reactome | Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites

Schema > Reaction > Entries

Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites Show undefined attributes

catalystActivity	[CatalystActivity:10455638] calcium,diacylglycerol-dependent serine/threonine kinase activity of Activated conventional protein kinase C [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10475908
displayName	Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
eventOf	[Pathway:R-SSC-416993] Trafficking of GluR2-containing AMPA receptors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-416985] Trafficking of GluR2-containing AMPA receptors to synapse - Sus scrofa [Reaction:R-SSC-421007] Endocytosis of Ca impermeable AMPA receptors - Sus scrofa
inferredFrom	[Reaction:R-HSA-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites - Homo sapiens
input	[Complex:R-SSC-416629] AP2 complex [endocytic vesicle membrane] [SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-SSC-416323] Ca impermeable AMPA receptors [endocytic vesicle membrane] [DefinedSet:R-SSC-416636] GRIP1/GRIP2 [cytosol] [EntityWithAccessionedSequence:R-SSC-417017] PICK1 [endocytic vesicle membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-416629] AP2 complex [endocytic vesicle membrane] [DefinedSet:R-SSC-399713] Ca impermeable AMPA receptors [plasma membrane] [DefinedSet:R-SSC-416631] GRIP1/GRIP2 [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol] [EntityWithAccessionedSequence:R-SSC-416989] PICK1 [plasma membrane]
precedingEvent	[Reaction:R-SSC-421007] Endocytosis of Ca impermeable AMPA receptors - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-416639
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-416993] Trafficking of GluR2-containing AMPA receptors
(precedingEvent)	[Reaction:R-SSC-416985] Trafficking of GluR2-containing AMPA receptors to synapse [Reaction:R-SSC-421007] Endocytosis of Ca impermeable AMPA receptors
(inferredTo)	[Reaction:R-HSA-416639] Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites