Reactome | Activation of PAK by Rac1

Schema > Reaction > Entries

Activation of PAK by Rac1 Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10756487
displayName	Activation of PAK by Rac1
eventOf	[Pathway:R-GGA-399954] Sema3A PAK dependent Axon repulsion - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-399939] Autophosphorylation of PAK - Gallus gallus
inferredFrom	[Reaction:R-HSA-399930] Activation of PAK by Rac1 - Homo sapiens
input	[DefinedSet:R-GGA-399856] PAK1,2,3 dimer [cytosol] [Complex:R-GGA-399872] Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Activation of PAK by Rac1
output	[DefinedSet:R-GGA-390765] PAK1,2,3 [cytosol] [Complex:R-GGA-399876] Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-399930
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-399954] Sema3A PAK dependent Axon repulsion
(precedingEvent)	[Reaction:R-GGA-399939] Autophosphorylation of PAK
(inferredTo)	[Reaction:R-HSA-399930] Activation of PAK by Rac1

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