Reactome | 5-HT2 receptor can bind serotonin

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5-HT2 receptor can bind serotonin Show undefined attributes

authored	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
dbId	390930
displayName	5-HT2 receptor can bind serotonin
edited	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
eventOf	[Pathway:R-HSA-390666] Serotonin receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq - Homo sapiens
input	[SimpleEntity:R-ALL-114523] 5HT [extracellular region] [DefinedSet:R-HSA-391030] HTR2A-C [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:391032] Genomic organisation and functional expression of the gene encoding the human serotonin 5-HT2C receptor [LiteratureReference:391013] Cloning and functional characterization of the human 5-HT2B serotonin receptor [LiteratureReference:390978] Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor [LiteratureReference:390945] Genomic organization, coding sequence and functional expression of human 5-HT2 and 5-HT1A receptor genes [LiteratureReference:390952] Receptor subtype and density determine the coupling repertoire of the 5-HT2 receptor subfamily
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	5-HT2 receptor can bind serotonin
orthologousEvent	[Reaction:R-CEL-390930] 5-HT2 receptor can bind serotonin - Caenorhabditis elegans [Reaction:R-DME-390930] 5-HT2 receptor can bind serotonin - Drosophila melanogaster [Reaction:R-GGA-390930] 5-HT2 receptor can bind serotonin - Gallus gallus [Reaction:R-XTR-390930] 5-HT2 receptor can bind serotonin - Xenopus tropicalis [Reaction:R-DRE-390930] 5-HT2 receptor can bind serotonin - Danio rerio [Reaction:R-SSC-390930] 5-HT2 receptor can bind serotonin - Sus scrofa [Reaction:R-BTA-390930] 5-HT2 receptor can bind serotonin - Bos taurus [Reaction:R-CFA-390930] 5-HT2 receptor can bind serotonin - Canis familiaris [Reaction:R-RNO-390930] 5-HT2 receptor can bind serotonin - Rattus norvegicus [Reaction:R-MMU-390930] 5-HT2 receptor can bind serotonin - Mus musculus
output	[Complex:R-HSA-390951] HTR2A-C:5HT [plasma membrane]
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392262] D'Eustachio, P, 2009-03-02 09:24:35
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-390930
summation	[Summation:390973] The 5-HT-2 receptors mediate many of the central and periphe...
updateTrackers	[UpdateTracker:9791408] Update Tracker - [Reaction:390930] 5-HT2 receptor can bind serotonin - v30:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9791408] Update Tracker - [Reaction:390930] 5-HT2 receptor can bind serotonin - v30:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-390666] Serotonin receptors
(precedingEvent)	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq

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