Reactome | 5-HT2 receptor can bind serotonin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10474989
displayName	5-HT2 receptor can bind serotonin
eventOf	[Pathway:R-SSC-390666] Serotonin receptors - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-390930] 5-HT2 receptor can bind serotonin - Homo sapiens
input	[SimpleEntity:R-ALL-114523] 5HT [extracellular region] [DefinedSet:R-SSC-391030] HTR2A-C [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	5-HT2 receptor can bind serotonin
output	[Complex:R-SSC-390951] HTR2A-C:5HT [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-390930
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-390666] Serotonin receptors
(inferredTo)	[Reaction:R-HSA-390930] 5-HT2 receptor can bind serotonin

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