Reactome | ADRA1A,B,D bind ADR,NAd

Schema > Reaction > Entries

ADRA1A,B,D bind ADR,NAd Show undefined attributes

authored	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
dbId	390641
displayName	ADRA1A,B,D bind ADR,NAd
edited	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
eventOf	[Pathway:R-HSA-390696] Adrenoceptors - Homo sapiens
followingEvent	[Reaction:R-HSA-751027] Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 - Homo sapiens [Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq - Homo sapiens
input	[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region] [DefinedSet:R-HSA-390684] ADRA1A,B,D [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:390683] Cloning, functional expression and tissue distribution of human cDNA for the alpha 1C-adrenergic receptor [LiteratureReference:390689] Genomic organization and expression of the human alpha 1B-adrenergic receptor [LiteratureReference:390624] Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ADRA1A,B,D bind ADR,NAd Alpha-1 adrenoceptors bind catecholamines
orthologousEvent	[Reaction:R-CEL-390641] ADRA1A,B,D bind ADR,NAd - Caenorhabditis elegans [Reaction:R-GGA-390641] ADRA1A,B,D bind ADR,NAd - Gallus gallus [Reaction:R-XTR-390641] ADRA1A,B,D bind ADR,NAd - Xenopus tropicalis [Reaction:R-DRE-390641] ADRA1A,B,D bind ADR,NAd - Danio rerio [Reaction:R-SSC-390641] ADRA1A,B,D bind ADR,NAd - Sus scrofa [Reaction:R-BTA-390641] ADRA1A,B,D bind ADR,NAd - Bos taurus [Reaction:R-CFA-390641] ADRA1A,B,D bind ADR,NAd - Canis familiaris [Reaction:R-RNO-390641] ADRA1A,B,D bind ADR,NAd - Rattus norvegicus [Reaction:R-MMU-390641] ADRA1A,B,D bind ADR,NAd - Mus musculus
output	[Complex:R-HSA-390633] ADRA1A,B,D:ADR,NAd [plasma membrane]
precedingEvent	[Reaction:R-HSA-9623384] ?1-agonists bind ADRA1A,B,D - Homo sapiens
regulatedBy	[NegativeRegulation:9623360] Negative regulation by '?1-antagonists:ADRA1A,B,D [plasma membrane]' [PositiveRegulation:9623389] Positive regulation by '?1-agonists:ADRA1A,B,D [plasma membrane]'
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392262] D'Eustachio, P, 2009-03-02 09:24:35
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-390641
summation	[Summation:390679] The alpha-1 adrenoceptors are involved in smooth muscle cont...
updateTrackers	[UpdateTracker:9778741] Update Tracker - [Reaction:390641] ADRA1A,B,D bind ADR,NAd - v67:[addRegulator]

Referrals

(updatedInstance)	[UpdateTracker:9778741] Update Tracker - [Reaction:390641] ADRA1A,B,D bind ADR,NAd - v67:[addRegulator]
(hasEvent)	[Pathway:R-HSA-390696] Adrenoceptors
(precedingEvent)	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq [Reaction:R-HSA-751027] Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13