Reactome | Activated CEBPB stimulates transcription of CDKN2B

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Activated CEBPB stimulates transcription of CDKN2B Show undefined attributes

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3857349] Orlic-Milacic, M, 2013-07-09
dbId	3857348
displayName	Activated CEBPB stimulates transcription of CDKN2B
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP) - Homo sapiens
followingEvent	[Reaction:R-HSA-182594] Association of INK4 family proteins with CDK4/6 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2187305] CDKN2B gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3857340] Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activated CEBPB stimulates transcription of CDKN2B
output	[EntityWithAccessionedSequence:R-HSA-182586] CDKN2B [cytosol]
precedingEvent	[Reaction:R-HSA-3857345] Activated CEBPB binds CDKN2B promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-3857346] Positive gene expression regulation by 'p-T235,S321-CEBPB:CDKN2B Gene [nucleoplasm]'
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-3857348
summation	[Summation:3858386] Once bound to the CDKN2B promoter, CEBPB stimulates CKDN2B t...

Referrals

(hasEvent)	[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP)
(precedingEvent)	[Reaction:R-HSA-182594] Association of INK4 family proteins with CDK4/6

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