Reactome | Activated CEBPB binds CDKN2B promoter

Schema > Reaction > Entries

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3857349] Orlic-Milacic, M, 2013-07-09
dbId	3857345
displayName	Activated CEBPB binds CDKN2B promoter
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP) - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-3857348] Activated CEBPB stimulates transcription of CDKN2B - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-2187305] CDKN2B gene [nucleoplasm] [Complex:R-HSA-3857334] p-T235,S321-CEBPB homodimer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3857340] Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activated CEBPB binds CDKN2B promoter
output	[Complex:R-HSA-3857347] p-T235,S321-CEBPB:CDKN2B Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-3857336] CEBPB homodimerization - Homo sapiens
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3857345
summation	[Summation:3858372] The CEBPB transcription factor, activated by oncogenic RAS s...

(hasEvent)	[Pathway:R-HSA-2559582] Senescence-Associated Secretory Phenotype (SASP)
(precedingEvent)	[BlackBoxEvent:R-HSA-3857348] Activated CEBPB stimulates transcription of CDKN2B

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