Reactome | Translocation of PDGF from ER to Golgi

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Translocation of PDGF from ER to Golgi Show undefined attributes

authored	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:382060] Garapati, P V, 2008-11-21 20:21:25
dbId	382053
displayName	Translocation of PDGF from ER to Golgi
edited	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
eventOf	[Pathway:R-HSA-186797] Signaling by PDGF - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-382057] Release of novel PDGFs as latent factors - Homo sapiens [Reaction:R-HSA-8865275] PDGF-BB clevage by Furin - Homo sapiens [Reaction:R-HSA-8865276] PDGF-AB clevage by Furin - Homo sapiens [Reaction:R-HSA-186785] PDGF-AA clevage by Furin - Homo sapiens
input	[DefinedSet:R-HSA-381936] PDGF precursor dimers (AA, BB, A/B, CC, DD) [endoplasmic reticulum lumen]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:380776] PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly [LiteratureReference:380726] The PDGF family: four gene products form five dimeric isoforms
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Translocation of PDGF from ER to Golgi
orthologousEvent	[Reaction:R-CEL-382053] Translocation of PDGF from ER to Golgi - Caenorhabditis elegans [Reaction:R-DME-382053] Translocation of PDGF from ER to Golgi - Drosophila melanogaster [Reaction:R-GGA-382053] Translocation of PDGF from ER to Golgi - Gallus gallus [Reaction:R-XTR-382053] Translocation of PDGF from ER to Golgi - Xenopus tropicalis [Reaction:R-DRE-382053] Translocation of PDGF from ER to Golgi - Danio rerio [Reaction:R-SSC-382053] Translocation of PDGF from ER to Golgi - Sus scrofa [Reaction:R-BTA-382053] Translocation of PDGF from ER to Golgi - Bos taurus [Reaction:R-CFA-382053] Translocation of PDGF from ER to Golgi - Canis familiaris [Reaction:R-RNO-382053] Translocation of PDGF from ER to Golgi - Rattus norvegicus [Reaction:R-MMU-382053] Translocation of PDGF from ER to Golgi - Mus musculus
output	[DefinedSet:R-HSA-381926] PDGF precursor dimers (AA, BB, A/B, CC, DD) [Golgi membrane]
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:382617] Heldin, CH, 2008-11-23 19:29:34
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-382053
summation	[Summation:381891] All the newly synthesized PDGF chains are dimerized in the E...

Referrals

(hasEvent)	[Pathway:R-HSA-186797] Signaling by PDGF
(precedingEvent)	[BlackBoxEvent:R-HSA-382057] Release of novel PDGFs as latent factors [Reaction:R-HSA-8865275] PDGF-BB clevage by Furin [Reaction:R-HSA-8865276] PDGF-AB clevage by Furin [Reaction:R-HSA-186785] PDGF-AA clevage by Furin