Reactome | Release of docked serotonin loaded synaptic vesicle

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Release of docked serotonin loaded synaptic vesicle Show undefined attributes

authored	[InstanceEdit:372555] Mahajan, SS, 2008-06-26 19:01:12
catalystActivity	[CatalystActivity:380904] SNARE binding activity of Docked serotonin loaded synaptic vesicle [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:374940] clathrin-sculpted monoamine transport vesicle membrane [Compartment:70101] cytosol
created	[InstanceEdit:380899] Mahajan, SS, 2008-11-18 00:00:02
dbId	380901
displayName	Release of docked serotonin loaded synaptic vesicle
edited	[InstanceEdit:447013] Gillespie, ME, 2009-11-19
eventOf	[Pathway:R-HSA-181429] Serotonin Neurotransmitter Release Cycle - Homo sapiens
followingEvent	[Reaction:R-HSA-9693347] HTR1A binds 5HT - Homo sapiens [Reaction:R-HSA-390929] HTR1 and 5A receptors can bind serotonin - Homo sapiens
input	[Complex:R-HSA-380900] Docked serotonin loaded synaptic vesicle [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:210479] Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis [LiteratureReference:210436] How synaptotagmin promotes membrane fusion [LiteratureReference:349555] Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Release of docked serotonin loaded synaptic vesicle
orthologousEvent	[Reaction:R-CEL-380901] Release of docked serotonin loaded synaptic vesicle - Caenorhabditis elegans [Reaction:R-DME-380901] Release of docked serotonin loaded synaptic vesicle - Drosophila melanogaster [Reaction:R-SSC-380901] Release of docked serotonin loaded synaptic vesicle - Sus scrofa [Reaction:R-BTA-380901] Release of docked serotonin loaded synaptic vesicle - Bos taurus [Reaction:R-RNO-380901] Release of docked serotonin loaded synaptic vesicle - Rattus norvegicus [Reaction:R-MMU-380901] Release of docked serotonin loaded synaptic vesicle - Mus musculus
output	[SimpleEntity:R-ALL-114523] 5HT [extracellular region] [EntityWithAccessionedSequence:R-HSA-210385] CPLX1 [cytosol] [EntityWithAccessionedSequence:R-HSA-210461] RAB3A [plasma membrane] [Complex:R-HSA-210374] RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] [EntityWithAccessionedSequence:R-HSA-374907] SLC18A2 [plasma membrane] [Complex:R-HSA-210441] SNARE complex [plasma membrane] [EntityWithAccessionedSequence:R-HSA-210514] STXBP1-1 [cytosol] [CandidateSet:R-HSA-380576] Synapsin [clathrin-sculpted monoamine transport vesicle membrane] [EntityWithAccessionedSequence:R-HSA-168786] SYT1 [plasma membrane]
precedingEvent	[Reaction:R-HSA-380905] Serotonin loaded synaptic vesicle docking and priming - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:386898] Restituito, S, 2008-11-27 12:38:49
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-380901
summation	[Summation:380875] The trimeric complex formed between V-SNARE (VAMP) and the T...
updateTrackers	[UpdateTracker:9786677] Update Tracker - [Reaction:380901] Release of docked serotonin loaded synaptic vesicle - v49:[add_removeOutput] [UpdateTracker:9791465] Update Tracker - [Reaction:380901] Release of docked serotonin loaded synaptic vesicle - v30:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9786677] Update Tracker - [Reaction:380901] Release of docked serotonin loaded synaptic vesicle - v49:[add_removeOutput] [UpdateTracker:9791465] Update Tracker - [Reaction:380901] Release of docked serotonin loaded synaptic vesicle - v30:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-181429] Serotonin Neurotransmitter Release Cycle
(precedingEvent)	[Reaction:R-HSA-9693347] HTR1A binds 5HT [Reaction:R-HSA-390929] HTR1 and 5A receptors can bind serotonin

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