Reactome | Somatostatin receptors bind somatostatin and cortistatin

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Somatostatin receptors bind somatostatin and cortistatin Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:374748] Jassal, Bijay, 2008-07-30
dbId	374758
displayName	Somatostatin receptors bind somatostatin and cortistatin
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[DefinedSet:R-HSA-374746] Somatostatin receptors [plasma membrane] [DefinedSet:R-HSA-8849391] Somatostatin, cortistatin [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374767] Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney [LiteratureReference:374734] Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase [LiteratureReference:374760] Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Somatostatin receptors bind somatostatin and cortistatin
orthologousEvent	[Reaction:R-GGA-374758] Somatostatin receptors bind somatostatin and cortistatin - Gallus gallus [Reaction:R-XTR-374758] Somatostatin receptors bind somatostatin and cortistatin - Xenopus tropicalis [Reaction:R-DRE-374758] Somatostatin receptors bind somatostatin and cortistatin - Danio rerio [Reaction:R-SSC-374758] Somatostatin receptors bind somatostatin and cortistatin - Sus scrofa [Reaction:R-BTA-374758] Somatostatin receptors bind somatostatin and cortistatin - Bos taurus [Reaction:R-CFA-374758] Somatostatin receptors bind somatostatin and cortistatin - Canis familiaris [Reaction:R-RNO-374758] Somatostatin receptors bind somatostatin and cortistatin - Rattus norvegicus [Reaction:R-MMU-374758] Somatostatin receptors bind somatostatin and cortistatin - Mus musculus
output	[Complex:R-HSA-374763] Somatostatin receptor:somatostatin [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-374758
summation	[Summation:374730] Somatostatin (growth hormone inhibiting hormone, GHIH; somat...
updateTrackers	[UpdateTracker:9783571] Update Tracker - [Reaction:374758] Somatostatin receptors bind somatostatin and cortistatin - v56:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9783571] Update Tracker - [Reaction:374758] Somatostatin receptors bind somatostatin and cortistatin - v56:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi