Reactome | G protein-coupled estrogen receptor 1 binds estrogen non-classically

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G protein-coupled estrogen receptor 1 binds estrogen non-classically Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:374171] Jassal, Bijay, 2008-07-28
dbId	374207
displayName	G protein-coupled estrogen receptor 1 binds estrogen non-classically
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[SimpleEntity:R-ALL-374146] ESTG [extracellular region] [EntityWithAccessionedSequence:R-HSA-374191] GPER1 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374202] Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	G protein-coupled estrogen receptor 1 binds estrogen non-classically
orthologousEvent	[Reaction:R-GGA-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Gallus gallus [Reaction:R-XTR-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Xenopus tropicalis [Reaction:R-DRE-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Danio rerio [Reaction:R-SSC-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Sus scrofa [Reaction:R-CFA-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Canis familiaris [Reaction:R-RNO-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Rattus norvegicus [Reaction:R-MMU-374207] G protein-coupled estrogen receptor 1 binds estrogen non-classically - Mus musculus
output	[Complex:R-HSA-374150] GPER1:ESTG [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-374207
summation	[Summation:374167] G protein-coupled estrogen receptor 1 (GPER; CEPR; G-protein...

Referrals

(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi

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