SLC38A2 (ATA2)-mediated uptake of neutral amino acids

Stable Identifier
R-HSA-352108
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC38A2 (ATA2), associated with the plasma membrane, mediates the uptake of neutral amino acids, especially alanine, asparagine, glutamine, glycine, leucine, methionine, proline, and threonine in a sodium ion-dependent transport process. Northern blotting experiments indicate gene expression in placenta and heart, and at lower levels in other tissues including brain, lung, skeletal muscle, spleen, stomach, testis, kidney, and intestine (Hatanaka et al. 2000).

Literature References
PubMed ID Title Journal Year
10930503 Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

Hatanaka, T, Huang, W, Wang, H, Sugawara, M, Prasad, PD, Leibach, FH, Ganapathy, V

Biochim Biophys Acta 2000
Participants
Participant Of
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Catalyst Activity
Title
amino acid transmembrane transporter activity of SLC38A2 [plasma membrane]
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