Reactome | 2xHC-TXN2 [mitochondrial matrix]

Schema > EntityWithAccessionedSequence > Entries

2xHC-TXN2 [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-HSA-3323050] TXNRD2 catalyzes the reduction of TXN2 by NADPH - Homo sapiens
created	[InstanceEdit:3323020] May, B, 2013-05-09
dbId	3323059
deleted	[Deleted:9766429] Deletion of instance: 9035482
displayName	2xHC-TXN2 [mitochondrial matrix]
endCoordinate	166
hasModifiedResidue	[IntraChainCrosslinkedResidue:3323019] Intra-chain Crosslink via L-cystine (cross-link) at 90 and 93
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-3323059] Txn2 [mitochondrial matrix] - Mus musculus [EntityWithAccessionedSequence:R-RNO-3323059] Txn2 [mitochondrial matrix] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-3323059] TXN2 [mitochondrial matrix] - Bos taurus [EntityWithAccessionedSequence:R-SSC-3323059] TXN2 [mitochondrial matrix] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-3323059] txn2 [mitochondrial matrix] - Danio rerio [EntityWithAccessionedSequence:R-XTR-3323059] txn2 [mitochondrial matrix] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-3323059] TXN2 [mitochondrial matrix] - Gallus gallus [EntityWithAccessionedSequence:R-DME-3323059] Dmel\CG8993 [mitochondrial matrix] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-3323059] trx-2 [mitochondrial matrix] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-3323059] 2xHC-TXN2 [mitochondrial matrix] - Dictyostelium discoideum
literatureReference	[LiteratureReference:3322999] Crystal structures of oxidized and reduced forms of human mitochondrial thioredoxin 2
maxDepth	1
modified	[InstanceEdit:3697905] May, B, 2013-06-09
name	2xHC-TXN2 TXN2 oxidized Thioredoxin, mitochondrial THIOM_HUMAN
producedByEvent	[Reaction:R-HSA-3697894] PRDX5 reduces peroxynitrite to nitrite using TXN2 - Homo sapiens [Reaction:R-HSA-3322995] PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O - Homo sapiens [Reaction:R-HSA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q99757] UniProt:Q99757 TXN2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3323059
startCoordinate	60

Referrals

(replacementInstances)	[Deleted:9766429] Deletion of instance: 9035482
(output)	[Reaction:R-HSA-3697894] PRDX5 reduces peroxynitrite to nitrite using TXN2 [Reaction:R-HSA-3322995] PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O [Reaction:R-HSA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST
(input)	[Reaction:R-HSA-3323050] TXNRD2 catalyzes the reduction of TXN2 by NADPH