Reactome | trx-2 [mitochondrial matrix]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-CEL-3323050] TXNRD2 catalyzes the reduction of TXN2 by NADPH - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10960885
displayName	trx-2 [mitochondrial matrix]
endCoordinate	166
hasModifiedResidue	[IntraChainCrosslinkedResidue:10960883] Intra-chain Crosslink via L-cystine (cross-link) at 90 and 93 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-3323059] 2xHC-TXN2 [mitochondrial matrix] - Homo sapiens
maxDepth	1
name	trx-2 2xHC-TXN2 Q17424
producedByEvent	[Reaction:R-CEL-3322995] PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O - Caenorhabditis elegans [Reaction:R-CEL-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Caenorhabditis elegans
referenceEntity	[ReferenceGeneProduct:uniprot:Q17424] UniProt:Q17424
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-3323059
startCoordinate	60

(output)	[Reaction:R-CEL-3322995] PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O [Reaction:R-CEL-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST
(input)	[Reaction:R-CEL-3323050] TXNRD2 catalyzes the reduction of TXN2 by NADPH
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-3323059] 2xHC-TXN2 [mitochondrial matrix]

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