Reactome | Glycogen synthesis

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Glycogen synthesis Show undefined attributes

authored	[InstanceEdit:70154] 2003-02-15 00:00:00
created	[InstanceEdit:3322072] D'Eustachio, P, 2013-05-02
crossReference	[DatabaseIdentifier:12819595] BioModels Database:BIOMD0000000579
dbId	3322077
deleted	[Deleted:3698013] Deletion of instance: 70302
displayName	Glycogen synthesis
doi	10.3180/REACT_169208.2
edited	[InstanceEdit:8982493] D'Eustachio, Peter, 2017-03-17
eventOf	[Pathway:R-HSA-8982491] Glycogen metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:19479] glycogen biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9638127] PGM1:Mg2+ isomerises G6P to G1P - Homo sapiens [Reaction:R-HSA-70286] UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose - Homo sapiens [Reaction:R-HSA-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Homo sapiens [Reaction:R-HSA-3322003] Autoglucosylation of GYG1 complexed with GYS1-b - Homo sapiens [Reaction:R-HSA-3322014] Autoglucosylation of GYG2 complexed with GYS2-a - Homo sapiens [Reaction:R-HSA-3322019] Autoglucosylation of GYG2 complexed with GYS2-b - Homo sapiens [Reaction:R-HSA-3322001] GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 - Homo sapiens [Reaction:R-HSA-3322041] Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 - Homo sapiens [Reaction:R-HSA-3322009] GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 - Homo sapiens [Reaction:R-HSA-3322005] GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a - Homo sapiens [Reaction:R-HSA-3322057] GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b - Homo sapiens [Reaction:R-HSA-3322016] GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a - Homo sapiens [Reaction:R-HSA-3781023] PPP1R3C binds to glycogen:GYG1:GYS1 - Homo sapiens [Reaction:R-HSA-3780997] PPP1R3C binds to glycogen:GYG2:GYS2 - Homo sapiens [Reaction:R-HSA-3781024] GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 - Homo sapiens [Reaction:R-HSA-3780994] GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 - Homo sapiens [Reaction:R-HSA-3781001] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex - Homo sapiens [Reaction:R-HSA-3781021] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex - Homo sapiens [Reaction:R-HSA-3781018] EPM2A dimer dephosphorylates phosphoglycogen-GYG1 - Homo sapiens [Reaction:R-HSA-3781011] EPM2A dimer dephosphorylates phosphoglycogen-GYG2 - Homo sapiens [BlackBoxEvent:R-HSA-3781009] NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 - Homo sapiens [BlackBoxEvent:R-HSA-3780995] NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
literatureReference	[LiteratureReference:3322029] Glucokinase and molecular aspects of liver glycogen metabolism [LiteratureReference:3322074] Specific features of glycogen metabolism in the liver [LiteratureReference:3322039] Glycogen and its metabolism: some new developments and old themes
maxDepth	2
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Glycogen synthesis
orthologousEvent	[Pathway:R-BTA-3322077] Glycogen synthesis - Bos taurus [Pathway:R-MMU-3322077] Glycogen synthesis - Mus musculus [Pathway:R-RNO-3322077] Glycogen synthesis - Rattus norvegicus [Pathway:R-CFA-3322077] Glycogen synthesis - Canis familiaris [Pathway:R-SSC-3322077] Glycogen synthesis - Sus scrofa [Pathway:R-DRE-3322077] Glycogen synthesis - Danio rerio [Pathway:R-XTR-3322077] Glycogen synthesis - Xenopus tropicalis [Pathway:R-GGA-3322077] Glycogen synthesis - Gallus gallus [Pathway:R-DME-3322077] Glycogen synthesis - Drosophila melanogaster [Pathway:R-CEL-3322077] Glycogen synthesis - Caenorhabditis elegans [Pathway:R-DDI-3322077] Glycogen synthesis - Dictyostelium discoideum [Pathway:R-SPO-3322077] Glycogen synthesis - Schizosaccharomyces pombe [Pathway:R-SCE-3322077] Glycogen synthesis - Saccharomyces cerevisiae
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2003-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4006079] Jassal, B, 2013-07-26 [InstanceEdit:9953436] Hill, David P, 2025-06-02
revised	[InstanceEdit:453329] D'Eustachio, P, 2010-01-21 [InstanceEdit:4416359] D'Eustachio, P, 2013-08-25 [InstanceEdit:5333089] D'Eustachio, Peter, 2014-02-18
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-3322077
summation	[Summation:3322073] Glycogen, a highly branched glucose polymer, is formed and b...
updateTrackers	[UpdateTracker:9784140] Update Tracker - [Pathway:3322077] Glycogen synthesis - v54:[updateContainedRLE] [UpdateTracker:9777859] Update Tracker - [Pathway:3322077] Glycogen synthesis - v68:[addHasEvent] [UpdateTracker:9774836] Update Tracker - [Pathway:3322077] Glycogen synthesis - v81:[removeHasEvent, updateContainedRLE] [UpdateTracker:9775784] Update Tracker - [Pathway:3322077] Glycogen synthesis - v78:[updateContainedRLE] [UpdateTracker:9786757] Update Tracker - [Pathway:3322077] Glycogen synthesis - v48:[updateContainedRLE] [UpdateTracker:9783809] Update Tracker - [Pathway:3322077] Glycogen synthesis - v55:[updateContainedRLE] [UpdateTracker:9777724] Update Tracker - [Pathway:3322077] Glycogen synthesis - v69:[addHasEvent]

Referrals

(hasEvent)	[Pathway:R-HSA-8982491] Glycogen metabolism
(replacementInstances)	[Deleted:3698013] Deletion of instance: 70302
(updatedInstance)	[UpdateTracker:9784140] Update Tracker - [Pathway:3322077] Glycogen synthesis - v54:[updateContainedRLE] [UpdateTracker:9777859] Update Tracker - [Pathway:3322077] Glycogen synthesis - v68:[addHasEvent] [UpdateTracker:9774836] Update Tracker - [Pathway:3322077] Glycogen synthesis - v81:[removeHasEvent, updateContainedRLE] [UpdateTracker:9775784] Update Tracker - [Pathway:3322077] Glycogen synthesis - v78:[updateContainedRLE] [UpdateTracker:9786757] Update Tracker - [Pathway:3322077] Glycogen synthesis - v48:[updateContainedRLE] [UpdateTracker:9783809] Update Tracker - [Pathway:3322077] Glycogen synthesis - v55:[updateContainedRLE] [UpdateTracker:9777724] Update Tracker - [Pathway:3322077] Glycogen synthesis - v69:[addHasEvent]

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