Reactome | Autoglucosylation of GYG1 complexed with GYS1-a

Schema > Reaction > Entries

Autoglucosylation of GYG1 complexed with GYS1-a Show undefined attributes

catalystActivity	[CatalystActivity:3322020] glycogenin glucosyltransferase activity of GYG1:GYS1-a tetramer [cytosol]
catalystActivityReference	[CatalystActivityReference:9643387] glycogenin glucosyltransferase activity of GYG1:GYS1-a tetramer [cytosol] Glycogenin-1 deficiency and inactivated priming of glycogen synthesis
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3322034] D'Eustachio, P, 2013-05-02
crossReference	[DatabaseIdentifier:9931454] RHEA:23361
dbId	3322025
deleted	[Deleted:3698018] Deletion of instance: 70290
diseaseReaction	[FailedReaction:R-HSA-3814838] Defective GYG1 is not autoglucosyolated - Homo sapiens
displayName	Autoglucosylation of GYG1 complexed with GYS1-a
eventOf	[Pathway:R-HSA-3322077] Glycogen synthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-3322001] GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 - Homo sapiens
input	[Complex:R-HSA-3322050] GYG1:GYS1-a tetramer [cytosol] 8 × [SimpleEntity:R-ALL-29410] UDP-Glc [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3322015] Glycogenin-1 deficiency and inactivated priming of glycogen synthesis [LiteratureReference:3322039] Glycogen and its metabolism: some new developments and old themes
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Autoglucosylation of GYG1 complexed with GYS1-a L-tyrosyl-(glycogenin) + UDP-alpha-D-glucose => alpha-D-glucosyl-L-tyrosyl-(glycogenin) + UDP + H(+) 8 UDP-glucose + GYG1 => 8 UDP + oligoGlc-GYG1 (GYS1-a)
orthologousEvent	[Reaction:R-BTA-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Bos taurus [Reaction:R-SCE-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Saccharomyces cerevisiae [Reaction:R-CEL-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Caenorhabditis elegans [Reaction:R-DME-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Drosophila melanogaster [Reaction:R-DRE-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Danio rerio [Reaction:R-SSC-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Sus scrofa [Reaction:R-CFA-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Canis familiaris [Reaction:R-RNO-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Rattus norvegicus [Reaction:R-MMU-3322025] Autoglucosylation of GYG1 complexed with GYS1-a - Mus musculus
output	8 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [Complex:R-HSA-3322035] oligoGlc-GYG1:GYS1-a tetramer [cytosol] 8 × [SimpleEntity:R-ALL-110096] UDP [cytosol]
precedingEvent	[Reaction:R-HSA-70286] UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose - Homo sapiens
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821385] four stars
reviewed	[InstanceEdit:4006079] Jassal, B, 2013-07-26
revised	[InstanceEdit:3322070] D'Eustachio, P, 2013-05-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3322025
summation	[Summation:3322026] Glycogenin 1 (GYG1) catalyzes its autoglycosylation reaction...
updateTrackers	[UpdateTracker:9939631] Update Tracker - [Reaction:3322025] Autoglucosylation of GYG1 complexed with GYS1-a - v92:[removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9939631] Update Tracker - [Reaction:3322025] Autoglucosylation of GYG1 complexed with GYS1-a - v92:[removeOutput]
(replacementInstances)	[Deleted:3698018] Deletion of instance: 70290
(normalReaction)	[FailedReaction:R-HSA-3814838] Defective GYG1 is not autoglucosyolated
(hasEvent)	[Pathway:R-HSA-3322077] Glycogen synthesis
(precedingEvent)	[Reaction:R-HSA-3322001] GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1

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