Reactome | NLRP4 [cytosol]

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NLRP4 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-3249384] NLRP4:DTX4:dsDNA:ZBP1:pS-172-TBK1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8948703] NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 - Homo sapiens [Reaction:R-HSA-3249392] NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 - Homo sapiens
created	[InstanceEdit:3249381] Shamovsky, V, 2013-04-09
dbId	3249366
displayName	NLRP4 [cytosol]
endCoordinate	994
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-3249366] NLRP4 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-3249366] Nlrp4 [cytosol] - Rattus norvegicus [GenomeEncodedEntity:R-BTA-3249366] Ghost homologue of NLRP4 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-3249366] NLRP4 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-3249366] NLRP4 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-3249366] LOC100491706 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-XTR-3249366-2] LOC108644478 [cytosol] - Xenopus tropicalis [DefinedSet:R-XTR-3249366-3] Homologues of NLRP4 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-3249366] NLRP3 [cytosol] - Gallus gallus
maxDepth	1
name	NLRP4 NACHT, LRR and PYD domains-containing protein 4
producedByEvent	[Reaction:R-HSA-3249386] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 - Homo sapiens [Reaction:R-HSA-8948709] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q96MN2] UniProt:Q96MN2 NLRP4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3249366
startCoordinate	1

Referrals

(input)	[Reaction:R-HSA-8948703] NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 [Reaction:R-HSA-3249392] NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3
(output)	[Reaction:R-HSA-3249386] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 [Reaction:R-HSA-8948709] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3
(hasComponent)	[Complex:R-HSA-3249384] NLRP4:DTX4:dsDNA:ZBP1:pS-172-TBK1 [cytosol] [Complex:R-HSA-8948707] NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane]

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