Reactome | Regulation by TREX1

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authored	[InstanceEdit:3065946] Shamovsky, V, 2013-02-06
created	[InstanceEdit:3248024] Shamovsky, V, 2013-04-05
dbId	3248023
displayName	Regulation by TREX1
edited	[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
eventOf	[Pathway:R-HSA-3134975] Regulation of innate immune responses to cytosolic DNA - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-3244605] TREX1 binds retroviral-derived DNA - Homo sapiens [BlackBoxEvent:R-HSA-3245943] Viral DNA cleavage by TREX1 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2014-07-15
literatureReference	[LiteratureReference:2453986] The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1 [LiteratureReference:3247911] Trex1 prevents cell-intrinsic initiation of autoimmunity
maxDepth	2
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	Regulation by TREX1
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3110284] D'Eustachio, P, 2013-02-11 [InstanceEdit:3597627] Jin, Lei, 2013-05-21 [InstanceEdit:3597624] Wu, Jiaxi, 2013-05-21
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-3248023
summation	[Summation:3248010] Three prime repair exonuclease 1 (TREX1) is a DNase type III...
updateTrackers	[UpdateTracker:9786409] Update Tracker - [Pathway:3248023] Regulation by TREX1 - v49:[modifyText]

(updatedInstance)	[UpdateTracker:9786409] Update Tracker - [Pathway:3248023] Regulation by TREX1 - v49:[modifyText]
(hasEvent)	[Pathway:R-HSA-3134975] Regulation of innate immune responses to cytosolic DNA

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