Reactome | TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter

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TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3215151] Orlic-Milacic, M, 2013-03-15
dbId	3215152
displayName	TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-3215144] TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-400139] CARM1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-381325] EP300 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3215141] GADD45A gene [nucleoplasm] [Complex:R-HSA-3222171] p-S15,S20-TP53 Tetramer [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3215140] PRMT1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3215145] Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
output	[Complex:R-HSA-3215149] p-S15,S20-TP53:EP300:PRMT1:CARM1:GADD45A Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6799246] CHEK1 phosphorylates TP53 - Homo sapiens [Reaction:R-HSA-69685] CHEK2 phosphorylates TP53 - Homo sapiens [Reaction:R-HSA-6805285] PLK3 phosphorylates TP53 - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3215152
summation	[Summation:6804119] TP53, together with chromatin modifying enzymes EP300, PRMT1...

Referrals

(hasEvent)	[Pathway:R-HSA-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
(precedingEvent)	[BlackBoxEvent:R-HSA-3215144] TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription

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