Reactome | p16INK4A mRNA [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[BlackBoxEvent:R-HSA-3209114] Translation of p16INK4A mRNA is inhibited by miR-24 - Homo sapiens
created	[InstanceEdit:3209104] Orlic-Milacic, M, 2013-03-01
dbId	3209105
displayName	p16INK4A mRNA [cytosol]
endCoordinate	1218
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-HSA-3209130] p16INK4A/p14ARF mRNA [cytosol] - Homo sapiens
modified	[InstanceEdit:9645190] Orlic-Milacic, Marija, 2019-05-06
name	p16INK4A mRNA CDKN2A Transcript Variant 1
producedByEvent	[BlackBoxEvent:R-HSA-3209098] p-T38-ETS1/p-T72-ETS2 stimulates transcription of p16INK4A mRNA - Homo sapiens [BlackBoxEvent:R-HSA-8853921] VENTX stimulates p16-INK4A transcription - Homo sapiens [BlackBoxEvent:R-HSA-3223200] Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription - Homo sapiens
referenceEntity	[ReferenceRNASequence:ensembl:ENST00000304494] ENSEMBL:ENST00000304494 CDKN2A
referenceType	ReferenceRNASequence
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3209105
startCoordinate	1
updateTrackers	[UpdateTracker:9900372] Update Tracker - [EntityWithAccessionedSequence:3209105] p16INK4A mRNA [cytosol] - v69:[modifyName]

(updatedInstance)	[UpdateTracker:9900372] Update Tracker - [EntityWithAccessionedSequence:3209105] p16INK4A mRNA [cytosol] - v69:[modifyName]
(output)	[BlackBoxEvent:R-HSA-3209098] p-T38-ETS1/p-T72-ETS2 stimulates transcription of p16INK4A mRNA [BlackBoxEvent:R-HSA-8853921] VENTX stimulates p16-INK4A transcription [BlackBoxEvent:R-HSA-3223200] Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription
(hasMember)	[DefinedSet:R-HSA-3209130] p16INK4A/p14ARF mRNA [cytosol]
(input)	[BlackBoxEvent:R-HSA-3209114] Translation of p16INK4A mRNA is inhibited by miR-24