Reactome | Beta-catenin migrates to the nucleus

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Beta-catenin migrates to the nucleus Show undefined attributes

authored	[InstanceEdit:3065946] Shamovsky, V, 2013-02-06
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:3134899] Shamovsky, V, 2013-02-13
dbId	3134914
displayName	Beta-catenin migrates to the nucleus
edited	[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
eventOf	[Pathway:R-HSA-3134973] LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production - Homo sapiens
followingEvent	[Reaction:R-HSA-3134883] Beta-catenin enhances association of IRF3 with CBP/p300 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3134933] p-S552-CTNNB1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3134936] The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway [LiteratureReference:3134912] beta-Catenin shows an overlapping sequence requirement but distinct molecular interactions for its bidirectional passage through nuclear pores
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Beta-catenin migrates to the nucleus
orthologousEvent	[BlackBoxEvent:R-MMU-3134914] Beta-catenin migrates to the nucleus - Mus musculus [BlackBoxEvent:R-CEL-3134914] Beta-catenin migrates to the nucleus - Caenorhabditis elegans [BlackBoxEvent:R-DME-3134914] Beta-catenin migrates to the nucleus - Drosophila melanogaster [BlackBoxEvent:R-GGA-3134914] Beta-catenin migrates to the nucleus - Gallus gallus [BlackBoxEvent:R-XTR-3134914] Beta-catenin migrates to the nucleus - Xenopus tropicalis [BlackBoxEvent:R-DRE-3134914] Beta-catenin migrates to the nucleus - Danio rerio [BlackBoxEvent:R-SSC-3134914] Beta-catenin migrates to the nucleus - Sus scrofa [BlackBoxEvent:R-BTA-3134914] Beta-catenin migrates to the nucleus - Bos taurus [BlackBoxEvent:R-CFA-3134914] Beta-catenin migrates to the nucleus - Canis familiaris [BlackBoxEvent:R-RNO-3134914] Beta-catenin migrates to the nucleus - Rattus norvegicus
output	[EntityWithAccessionedSequence:R-HSA-3134926] p-S552-CTNNB1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-3134904] Phosphorylation of beta-catenin at Ser552 - Homo sapiens
releaseDate	2013-06-11
requiredInputComponent	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3110284] D'Eustachio, P, 2013-02-11 [InstanceEdit:3597627] Jin, Lei, 2013-05-21 [InstanceEdit:3597624] Wu, Jiaxi, 2013-05-21
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-3134914
summation	[Summation:3134886] Phosphorylated ?-catenin migrates to the nucleus where it fu...
updateTrackers	[UpdateTracker:9864102] Update Tracker - [BlackBoxEvent:3134914] Beta-catenin migrates to the nucleus - v88:[modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9864102] Update Tracker - [BlackBoxEvent:3134914] Beta-catenin migrates to the nucleus - v88:[modifyText, removeLiteratureReference]
(hasEvent)	[Pathway:R-HSA-3134973] LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
(precedingEvent)	[Reaction:R-HSA-3134883] Beta-catenin enhances association of IRF3 with CBP/p300