Reactome | p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane]

Schema > Complex > Entries

p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2685694] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2730889] Recruitment of PAK to the membrane by binding active RAC1 - Homo sapiens
created	[InstanceEdit:2685710] Garapati, P V, 2012-12-03
dbId	2685706
displayName	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane]
hasComponent	[Complex:R-HSA-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [DefinedSet:R-HSA-2029115] p-VAV family [cytosol] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [Complex:R-HSA-442641] RAC1:GTP [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Mus musculus [Complex:R-RNO-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Rattus norvegicus [Complex:R-CFA-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Canis familiaris [Complex:R-BTA-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Bos taurus [Complex:R-SSC-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Sus scrofa [Complex:R-XTR-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Gallus gallus [Complex:R-DME-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Drosophila melanogaster
isChimeric	false
name	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP
producedByEvent	[Reaction:R-HSA-2730840] Activation of RAC1 by VAV - Homo sapiens [Reaction:R-HSA-2730856] Autophosphorylation of PAK - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2685706

Referrals

(output)	[Reaction:R-HSA-2730840] Activation of RAC1 by VAV [Reaction:R-HSA-2730856] Autophosphorylation of PAK
(input)	[Reaction:R-HSA-2730889] Recruitment of PAK to the membrane by binding active RAC1
(hasComponent)	[Complex:R-HSA-2685694] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane]

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