Reactome | EPH-Ephrin signaling

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EPH-Ephrin signaling Show undefined attributes

authored	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:2682322] Garapati, P V, 2012-11-29
dbId	2682334
displayName	EPH-Ephrin signaling
doi	10.3180/REACT_228170.1
edited	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
eventOf	[Pathway:R-HSA-422475] Axon guidance - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:186] ephrin receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-3928646] EPHAs bind EFNAs - Homo sapiens [Reaction:R-HSA-3928624] EPHBs bind EFNBs - Homo sapiens [Reaction:R-HSA-3928597] EPH:EFN dimers tetramerise - Homo sapiens [Polymerisation:R-HSA-3928591] EPH:EFN tetramers oligomerise - Homo sapiens [Reaction:R-HSA-3928578] EPH receptors autophosphorylate - Homo sapiens [Reaction:R-HSA-3928584] p-EPHs bind SRC,FYN,YES,LYN - Homo sapiens [Pathway:R-HSA-3928663] EPHA-mediated growth cone collapse - Homo sapiens [Pathway:R-HSA-3928662] EPHB-mediated forward signaling - Homo sapiens [Pathway:R-HSA-3928664] Ephrin signaling - Homo sapiens [Pathway:R-HSA-3928665] EPH-ephrin mediated repulsion of cells - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-03-29
literatureReference	[LiteratureReference:2682333] Eph/ephrin signaling: networks [LiteratureReference:5490280] Eph receptors at synapses: implications in neurodegenerative diseases
maxDepth	3
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	EPH-Ephrin signaling
orthologousEvent	[Pathway:R-SCE-2682334] EPH-Ephrin signaling - Saccharomyces cerevisiae [Pathway:R-DDI-2682334] EPH-Ephrin signaling - Dictyostelium discoideum [Pathway:R-CEL-2682334] EPH-Ephrin signaling - Caenorhabditis elegans [Pathway:R-DME-2682334] EPH-Ephrin signaling - Drosophila melanogaster [Pathway:R-GGA-2682334] EPH-Ephrin signaling - Gallus gallus [Pathway:R-XTR-2682334] EPH-Ephrin signaling - Xenopus tropicalis [Pathway:R-DRE-2682334] EPH-Ephrin signaling - Danio rerio [Pathway:R-SSC-2682334] EPH-Ephrin signaling - Sus scrofa [Pathway:R-BTA-2682334] EPH-Ephrin signaling - Bos taurus [Pathway:R-CFA-2682334] EPH-Ephrin signaling - Canis familiaris [Pathway:R-RNO-2682334] EPH-Ephrin signaling - Rattus norvegicus [Pathway:R-MMU-2682334] EPH-Ephrin signaling - Mus musculus
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-2682334
summation	[Summation:3928286] During the development process cell migration and adhesion a...
updateTrackers	[UpdateTracker:9780852] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v62:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780349] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v63:[updateContainedRLE, updateIndirectRLE] [UpdateTracker:9781601] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v60:[updateIndirectRLE] [UpdateTracker:9846641] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v84:[updateIndirectRLE] [UpdateTracker:9784723] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v53:[updateIndirectRLE]

Referrals

(updatedInstance)	[UpdateTracker:9780852] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v62:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9780349] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v63:[updateContainedRLE, updateIndirectRLE] [UpdateTracker:9781601] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v60:[updateIndirectRLE] [UpdateTracker:9846641] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v84:[updateIndirectRLE] [UpdateTracker:9784723] Update Tracker - [Pathway:2682334] EPH-Ephrin signaling - v53:[updateIndirectRLE]
(hasEncapsulatedEvent)	[Pathway:R-HSA-1483255] PI Metabolism
(hasEvent)	[Pathway:R-HSA-422475] Axon guidance

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