Reactome | CDK1 phosphorylates condensin I

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CDK1 phosphorylates condensin I Show undefined attributes

authored	[InstanceEdit:2525913] Orlic-Milacic, M, 2012-10-12
catalystActivity	[CatalystActivity:2311326] cyclin-dependent protein serine/threonine kinase activity of CCNB1,CCNB2:p-T161-CDK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2514846] Orlic-Milacic, M, 2012-10-10
dbId	2514854
displayName	CDK1 phosphorylates condensin I
edited	[InstanceEdit:2555383] Matthews, L, 2012-10-18 [InstanceEdit:2532796] D'Eustachio, P, 2012-10-19
eventOf	[Pathway:R-HSA-2514853] Condensation of Prometaphase Chromosomes - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2520883] Phosphorylated condensin I promotes condensation of prometaphase chromosomes - Homo sapiens
inferredFrom	[Reaction:R-XLA-2520871] Cdk1 phosphorylates condensin I - Xenopus laevis
input	6 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-1638143] Condensin I [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:2514841] Chromosome condensation by a human condensin complex in Xenopus egg extracts [LiteratureReference:2514849] Negative regulation of condensin I by CK2-mediated phosphorylation [LiteratureReference:2514845] Phosphorylation and activation of 13S condensin by Cdc2 in vitro [LiteratureReference:2525912] Phosphorylation of CAP-G is required for its chromosomal DNA localization during mitosis
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CDK1 phosphorylates condensin I
output	6 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-2520845] CDK1 Phosphorylated Condensin I [cytosol]
precedingEvent	[Reaction:R-HSA-2529015] Dephosphorylation of CK2-modified condensin I - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2580340] Anonymous, 2012-11-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2514854
summation	[Summation:2520872] CDK1 (CDC2) in complex with CCNB (cyclin B) phosphorylates c...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-2520883] Phosphorylated condensin I promotes condensation of prometaphase chromosomes
(hasEvent)	[Pathway:R-HSA-2514853] Condensation of Prometaphase Chromosomes
(inferredTo)	[Reaction:R-XLA-2520871] Cdk1 phosphorylates condensin I

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