Reactome | Aggrecan binds Hyaluronan and HAPLN1

Schema > Reaction > Entries

Aggrecan binds Hyaluronan and HAPLN1 Show undefined attributes

authored	[InstanceEdit:2976617] Jupe, S, 2013-01-10
category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2318670] Jupe, S, 2012-06-15
dbId	2318623
displayName	Aggrecan binds Hyaluronan and HAPLN1
edited	[InstanceEdit:3318356] Jupe, S, 2013-04-26
eventOf	[Pathway:R-HSA-3000178] ECM proteoglycans - Homo sapiens
input	[DefinedSet:R-HSA-2318622] Aggrecan [extracellular region] [Polymer:R-ALL-2160848] HA [extracellular region] [EntityWithAccessionedSequence:R-HSA-2299700] HAPLN1 [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2299683] Cartilage proteoglycan binding region and link protein. Radioimmunoassays and the detection of masked determinants in aggregates [LiteratureReference:2426493] Identification of hyaluronan-binding domains of aggrecan [LiteratureReference:2426522] The expression of functional link protein in a baculovirus system: analysis of mutants lacking the A, B and B' domains
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Aggrecan binds Hyaluronan and HAPLN1
orthologousEvent	[Reaction:R-GGA-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Gallus gallus [Reaction:R-DRE-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Danio rerio [Reaction:R-SSC-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Sus scrofa [Reaction:R-BTA-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Bos taurus [Reaction:R-CFA-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Canis familiaris [Reaction:R-RNO-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Rattus norvegicus [Reaction:R-MMU-2318623] Aggrecan binds Hyaluronan and HAPLN1 - Mus musculus
output	[Complex:R-HSA-2318621] Aggrecan:HA:HAPLN1 [extracellular region]
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3597636] Narayanan, Venkatesan, 2013-05-21 [InstanceEdit:3597676] Ricard-Blum, Sylvie, 2013-05-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2318623
summation	[Summation:2318707] In articular cartilage the major non-fibrous macromolecules ...

Referrals

(hasEvent)

[Pathway:R-HSA-3000178] ECM proteoglycans