Reactome | PLK1 hyperphosphorylates Condensin II complex

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PLK1 hyperphosphorylates Condensin II complex Show undefined attributes

authored	[InstanceEdit:3301857] Orlic-Milacic, M, 2013-04-22
catalystActivity	[CatalystActivity:2294577] protein serine/threonine kinase activity of p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2294582] Orlic-Milacic, M, 2012-05-31
dbId	2294580
displayName	PLK1 hyperphosphorylates Condensin II complex
edited	[InstanceEdit:3451184] Matthews, L, 2013-04-23
eventOf	[Pathway:R-HSA-2299718] Condensation of Prophase Chromosomes - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2294574] Condensin II-mediated condensation of prophase chromosomes - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-HSA-2294591] p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2294599] The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	PLK1 hyperphosphorylates Condensin II complex
orthologousEvent	[Reaction:R-BTA-2294580] PLK1 hyperphosphorylates Condensin II complex - Bos taurus [Reaction:R-DDI-2294580] PLK1 hyperphosphorylates Condensin II complex - Dictyostelium discoideum [Reaction:R-GGA-2294580] PLK1 hyperphosphorylates Condensin II complex - Gallus gallus [Reaction:R-XTR-2294580] PLK1 hyperphosphorylates Condensin II complex - Xenopus tropicalis [Reaction:R-DRE-2294580] PLK1 hyperphosphorylates Condensin II complex - Danio rerio [Reaction:R-SSC-2294580] PLK1 hyperphosphorylates Condensin II complex - Sus scrofa [Reaction:R-CFA-2294580] PLK1 hyperphosphorylates Condensin II complex - Canis familiaris [Reaction:R-RNO-2294580] PLK1 hyperphosphorylates Condensin II complex - Rattus norvegicus [Reaction:R-MMU-2294580] PLK1 hyperphosphorylates Condensin II complex - Mus musculus
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-HSA-2294604] Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2294590] PLK1 binds phosphorylated condensin II complex - Homo sapiens
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5085845] Longworth, MS, 2013-10-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2294580
summation	[Summation:2294597] Once PLK1 is recruited to the chromatin-bound condensin II c...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-2294574] Condensin II-mediated condensation of prophase chromosomes
(hasEvent)	[Pathway:R-HSA-2299718] Condensation of Prophase Chromosomes