Reactome | Tight Junction Complex:PARD6A:RHOA [cell junction]

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Tight Junction Complex:PARD6A:RHOA [cell junction] Show undefined attributes

compartment	[Compartment:204883] cell junction
componentOf	[Complex:R-HSA-2134509] Tight Junction Complex:TGFBR1:PARD6A:RHOA [cell junction] - Homo sapiens [Complex:R-HSA-2134522] Tight Junction Complex:TGFB1:TGFBR2:TGFBR1:PARD6A:RHOA [cell junction] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2134506] TGFBR1 is recruited to tight junctions by PARD6A - Homo sapiens
created	[InstanceEdit:2134512] Orlic-Milacic, M, 2012-02-23
dbId	2134514
displayName	Tight Junction Complex:PARD6A:RHOA [cell junction]
hasComponent	[EntityWithAccessionedSequence:R-HSA-2134486] ARHGEF18 [cell junction] [EntityWithAccessionedSequence:R-HSA-2134478] CGN [cell junction] [EntityWithAccessionedSequence:R-HSA-2134498] F11R [cell junction] [Complex:R-HSA-2133770] PARD3:PARD6A:PRKCZ [cell junction] [Complex:R-HSA-5665993] RHOA:GTP [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:876] plasma membrane
literatureReference	[LiteratureReference:2134508] Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis [LiteratureReference:2134494] Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin [LiteratureReference:419972] The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM) [LiteratureReference:419982] The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity
maxDepth	3
modified	[InstanceEdit:9026177] Orlic-Milacic, Marija, 2017-10-17
name	Tight Junction Complex:PARD6A:RHOA
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2134514
summation	[Summation:2134492] In this complex, PARD3:PARD6A:PRKCZ is bound to JAM-A. JAM-A...
updateTrackers	[UpdateTracker:9898370] Update Tracker - [Complex:2134514] Tight Junction Complex:PARD6A:RHOA [cell junction] - v63:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9898370] Update Tracker - [Complex:2134514] Tight Junction Complex:PARD6A:RHOA [cell junction] - v63:[add_removeHasComponent]
(input)	[Reaction:R-HSA-2134506] TGFBR1 is recruited to tight junctions by PARD6A
(hasComponent)	[Complex:R-HSA-2134509] Tight Junction Complex:TGFBR1:PARD6A:RHOA [cell junction] [Complex:R-HSA-2134522] Tight Junction Complex:TGFB1:TGFBR2:TGFBR1:PARD6A:RHOA [cell junction]

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