Reactome | CYP3A7 can 6beta-hydroxylate testosterone

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CYP3A7 can 6beta-hydroxylate testosterone Show undefined attributes

authored	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
catalystActivity	[CatalystActivity:213160] monooxygenase activity of Cytochrome P450 (CYP3A7 based) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:211969] Jassal, B, 2008-02-08 15:33:52
dbId	211882
displayName	CYP3A7 can 6beta-hydroxylate testosterone
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
eventOf	[Pathway:R-HSA-211981] Xenobiotics - Homo sapiens
input	[SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113534] O2 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-30321] TES [endoplasmic reticulum lumen]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:213139] Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	CYP3A7 can 6beta-hydroxylate testosterone
orthologousEvent	[Reaction:R-GGA-211882] CYP3A7 can 6beta-hydroxylate testosterone - Gallus gallus [Reaction:R-XTR-211882] CYP3A7 can 6beta-hydroxylate testosterone - Xenopus tropicalis [Reaction:R-DRE-211882] CYP3A7 can 6beta-hydroxylate testosterone - Danio rerio [Reaction:R-SSC-211882] CYP3A7 can 6beta-hydroxylate testosterone - Sus scrofa [Reaction:R-BTA-211882] CYP3A7 can 6beta-hydroxylate testosterone - Bos taurus [Reaction:R-CFA-211882] CYP3A7 can 6beta-hydroxylate testosterone - Canis familiaris [Reaction:R-RNO-211882] CYP3A7 can 6beta-hydroxylate testosterone - Rattus norvegicus [Reaction:R-MMU-211882] CYP3A7 can 6beta-hydroxylate testosterone - Mus musculus
output	[SimpleEntity:R-ALL-213144] 6BHT [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-211882
summation	[Summation:213165] CYP3A7 is only expressed in fetal liver and not in adults. I...

Referrals

(hasEvent)

[Pathway:R-HSA-211981] Xenobiotics