Reactome | CYP3A7 can 6beta-hydroxylate testosterone

Schema > Reaction > Entries

CYP3A7 can 6beta-hydroxylate testosterone Show undefined attributes

catalystActivity	[CatalystActivity:10128283] monooxygenase activity of Cytochrome P450 (CYP3A7 based) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10128285
displayName	CYP3A7 can 6beta-hydroxylate testosterone
eventOf	[Pathway:R-RNO-211981] Xenobiotics - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-211882] CYP3A7 can 6beta-hydroxylate testosterone - Homo sapiens
input	[SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113534] O2 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-30321] TES [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP3A7 can 6beta-hydroxylate testosterone
output	[SimpleEntity:R-ALL-213144] 6BHT [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-211882
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-211981] Xenobiotics
(inferredTo)	[Reaction:R-HSA-211882] CYP3A7 can 6beta-hydroxylate testosterone