CYP3A7 is only expressed in fetal liver and not in adults. It has lower biotransformation capability than other members of the CYP3A family such as 3A4 or 3A5 but possesses a similar broad specificity. CYP3A7 plays a major role in fetal steroid hydroxylation, an example being the 6beta-hydroxylation of testosterone.
Nakasa, H, Nakamura, H, Itahashi, K, Ishii, I, Fujiki, N, Kitada, M, Ohmori, S
monooxygenase activity of Cytochrome P450 (CYP3A7 based) [endoplasmic reticulum membrane]
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