Reactome | Interaction of Tie2 with Ang1

Schema > Reaction > Entries

Interaction of Tie2 with Ang1 Show undefined attributes

authored	[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:204777] Garapati, P V, 2007-12-03 09:53:12
dbId	204779
displayName	Interaction of Tie2 with Ang1
eventOf	[Pathway:R-HSA-210993] Tie2 Signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-204854] ANGPT1 [extracellular region] [EntityWithAccessionedSequence:R-HSA-197755] TEK [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:204795] Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region [LiteratureReference:204770] Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning [LiteratureReference:204866] The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development [LiteratureReference:210882] Angiopoietin and Tie signaling pathways in vascular development
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Interaction of Tie2 with Ang1
orthologousEvent	[Reaction:R-CEL-204779] Interaction of Tie2 with Ang1 - Caenorhabditis elegans [Reaction:R-DME-204779] Interaction of Tie2 with Ang1 - Drosophila melanogaster [Reaction:R-GGA-204779] Interaction of Tie2 with Ang1 - Gallus gallus [Reaction:R-XTR-204779] Interaction of Tie2 with Ang1 - Xenopus tropicalis [Reaction:R-DRE-204779] Interaction of Tie2 with Ang1 - Danio rerio [Reaction:R-SSC-204779] Interaction of Tie2 with Ang1 - Sus scrofa [Reaction:R-BTA-204779] Interaction of Tie2 with Ang1 - Bos taurus [Reaction:R-CFA-204779] Interaction of Tie2 with Ang1 - Canis familiaris [Reaction:R-RNO-204779] Interaction of Tie2 with Ang1 - Rattus norvegicus [Reaction:R-MMU-204779] Interaction of Tie2 with Ang1 - Mus musculus
output	[Complex:R-HSA-204807] ANGPT1:TEK [plasma membrane]
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-204779
summation	[Summation:210877] Tie receptors and their angiopoietin ligands play a critical...

Referrals

(hasEvent)	[Pathway:R-HSA-210993] Tie2 Signaling
(precedingEvent)	[Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex